LB11. A Single Dose of the MVA-BN Smallpox Vaccine Induces an Early Protective Antibody Response Similar to a Traditional Replicating Vaccine and Is Suitable for Emergency Scenario...

по Maclennan, Jane, Weidenthaler, Heinz, Pittman, Phillip, Schmidt, Darja, Chaplin, Paul
Опубликовано в: Open Forum Infect Dis (2019)

Genetic Adjuvantation of Recombinant MVA with CD40L Potentiates CD8 T Cell Mediated Immunity

по Lauterbach, Henning, Pätzold, Juliane, Kassub, Ronny, Bathke, Barbara, Brinkmann, Kay, Chaplin, Paul, Suter, Mark, Hochrein, Hubertus
Опубликовано 2013

Phase II Randomized, Double-Blinded Comparison of A Single High Dose (5×10(8) TCID(50)) of Modified Vaccinia Ankara Compared To A Standard Dose (1×10(8) TCID(50)) in Healthy Vaccin...

по Frey, Sharon E., Winokur, Patricia L., Hill, Heather, Goll, Johannes B., Chaplin, Paul, Belshe, Robert B.
Опубликовано 2014

Coexpression of Interleukin-12 Chains by a Self-Splicing Vector Increases the Protective Cellular Immune Response of DNA and Mycobacterium bovis BCG Vaccines against Mycobacterium...

по Palendira, Umaimainthan, Kamath, Arun T., Feng, Carl G., Martin, Ela, Chaplin, Paul J., Triccas, James A., Britton, Warwick J.
Опубликовано 2002

Immune Requirements of Post-Exposure Immunization with Modified Vaccinia Ankara of Lethally Infected Mice

по Lauterbach, Henning, Kassub, Ronny, Pätzold, Juliane, Körner, Jana, Brückel, Michael, Verschoor, Admar, Chaplin, Paul, Suter, Mark, Hochrein, Hubertus
Опубликовано 2010

Evaluation of the efficacy of modified vaccinia Ankara (MVA)/IMVAMUNE(®) against aerosolized rabbitpox virus in a rabbit model()

по Garza, Nicole L., Hatkin, Josh M., Livingston, Virginia, Nichols, Donald K., Chaplin, Paul J., Volkmann, Ariane, Fisher, Diana, Nalca, Aysegul
Опубликовано 2009

The Vaccinia Virus O1 Protein Is Required for Sustained Activation of Extracellular Signal-Regulated Kinase 1/2 and Promotes Viral Virulence

по Schweneker, Marc, Lukassen, Susanne, Späth, Michaela, Wolferstätter, Michael, Babel, Eveline, Brinkmann, Kay, Wielert, Ursula, Chaplin, Paul, Suter, Mark, Hausmann, Jürgen
Опубликовано 2012

A Novel Naturally Occurring Tandem Promoter in Modified Vaccinia Virus Ankara Drives Very Early Gene Expression and Potent Immune Responses

по Wennier, Sonia T., Brinkmann, Kay, Steinhäußer, Charlotte, Mayländer, Nicole, Mnich, Claudia, Wielert, Ursula, Dirmeier, Ulrike, Hausmann, Jürgen, Chaplin, Paul, Steigerwald, Robin
Опубликовано 2013

Survival of lethal poxvirus infection in mice depends on TLR9, and therapeutic vaccination provides protection

по Samuelsson, Christofer, Hausmann, Jürgen, Lauterbach, Henning, Schmidt, Michaela, Akira, Shizuo, Wagner, Hermann, Chaplin, Paul, Suter, Mark, O’Keeffe, Meredith, Hochrein, Hubertus
Опубликовано 2008

Immediate-Early Expression of a Recombinant Antigen by Modified Vaccinia Virus Ankara Breaks the Immunodominance of Strong Vector-Specific B8R Antigen in Acute and Memory CD8 T-Cel...

по Baur, Karen, Brinkmann, Kay, Schweneker, Marc, Pätzold, Juliane, Meisinger-Henschel, Christine, Hermann, Judith, Steigerwald, Robin, Chaplin, Paul, Suter, Mark, Hausmann, Jürgen
Опубликовано 2010

CD70 encoded by modified vaccinia virus Ankara enhances CD8 T‐cell‐dependent protective immunity in MHC class II‐deficient mice

по Bathke, Barbara, Pätzold, Juliane, Kassub, Ronny, Giessel, Raphael, Lämmermann, Kerstin, Hinterberger, Maria, Brinkmann, Kay, Chaplin, Paul, Suter, Mark, Hochrein, Hubertus, Lauterbach, Henning
Опубликовано в: Immunology (2018)

Targeting Improves the Efficacy of a DNA Vaccine against Corynebacterium pseudotuberculosis in Sheep

по Chaplin, Paul J., De Rose, Robert, Boyle, Jefferey S., McWaters, Peter, Kelly, Julie, Tennent, Jan M., Lew, Andrew M., Scheerlinck, Jean-Pierre Y.
Опубликовано 1999

A randomized, double-blind, dose-finding Phase II study to evaluate immunogenicity and safety of the third generation smallpox vaccine candidate IMVAMUNE®

по von Krempelhuber, Alfred, Vollmar, Jens, Pokorny, Rolf, Rapp, Petra, Wulff, Niels, Petzold, Barbara, Handley, Amanda, Mateo, Lyn, Siersbol, Henriette, Kollaritsch, Herwig, Chaplin, Paul
Опубликовано 2009

A major role for TLR8 in the recognition of vaccinia viral DNA by murine pDC?

по Bauer, Stefan, Bathke, Barbara, Lauterbach, Henning, Pätzold, Juliane, Kassub, Ronny, Luber, Christian A., Schlatter, Beatrix, Hamm, Svetlana, Chaplin, Paul, Suter, Mark, Hochrein, Hubertus
Опубликовано 2010

Introduction of the Six Major Genomic Deletions of Modified Vaccinia Virus Ankara (MVA) into the Parental Vaccinia Virus Is Not Sufficient To Reproduce an MVA-Like Phenotype in Cel...

по Meisinger-Henschel, Christine, Späth, Michaela, Lukassen, Susanne, Wolferstätter, Michael, Kachelriess, Heike, Baur, Karen, Dirmeier, Ulrike, Wagner, Markus, Chaplin, Paul, Suter, Mark, Hausmann, Jürgen
Опубликовано 2010

Safety, Immunogenicity, and Surrogate Markers of Clinical Efficacy for Modified Vaccinia Ankara as a Smallpox Vaccine in HIV-Infected Subjects

по Greenberg, Richard N., Overton, Edgar Turner, Haas, David W., Frank, Ian, Goldman, Mitchell, von Krempelhuber, Alfred, Virgin, Garth, Bädeker, Nicole, Vollmar, Jens, Chaplin, Paul
Опубликовано 2013

Recombinant Modified Vaccinia Virus Ankara Generating Excess Early Double-Stranded RNA Transiently Activates Protein Kinase R and Triggers Enhanced Innate Immune Responses

по Wolferstätter, Michael, Schweneker, Marc, Späth, Michaela, Lukassen, Susanne, Klingenberg, Marieken, Brinkmann, Kay, Wielert, Ursula, Lauterbach, Henning, Hochrein, Hubertus, Chaplin, Paul, Suter, Mark, Hausmann, Jürgen
Опубликовано в: J Virol (2014)

Cardiac Safety of Modified Vaccinia Ankara for Vaccination against Smallpox in a Young, Healthy Study Population

по Zitzmann-Roth, Eva-Maria, von Sonnenburg, Frank, de la Motte, Stephan, Arndtz-Wiedemann, Nathaly, von Krempelhuber, Alfred, Uebler, Nadine, Vollmar, Jens, Virgin, Garth, Chaplin, Paul
Опубликовано в: PLoS One (2015)

Intratumoral virotherapy with 4-1BBL armed modified vaccinia Ankara eradicates solid tumors and promotes protective immune memory

по Hinterberger, Maria, Giessel, Raphael, Fiore, Giovanna, Graebnitz, Fabienne, Bathke, Barbara, Wennier, Sonia, Chaplin, Paul, Melero, Ignacio, Suter, Mark, Lauterbach, Henning, Berraondo, Pedro, Hochrein, Hubertus, Medina-Echeverz, José
Опубликовано в: J Immunother Cancer (2021)

Clinical and Immunologic Responses to Multiple Doses of IMVAMUNE(®) (Modified Vaccinia Ankara) Followed by Dryvax(®) Challenge

по Frey, Sharon E., Newman, Frances K., Kennedy, Jeffrey S., Sobek, Vera, Ennis, Francis A., Hill, Heather, Yan, Lihan K., Chaplin, Paul, Vollmar, Jens, Chaitman, Bernard R., Belshe, Robert B.
Опубликовано 2007