Intratumoral virotherapy with 4-1BBL armed modified vaccinia Ankara eradicates solid tumors and promotes protective immune memory

Background Human cancers are extraordinarily heterogeneous in terms of tumor antigen expression, immune infiltration and composition. A common feature, however, is the host′s inability to mount potent immune responses that prevent tumor growth effectively. Often, naturally primed CD8(+) T cells agai...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:J Immunother Cancer
Main Authors: Hinterberger, Maria, Giessel, Raphael, Fiore, Giovanna, Graebnitz, Fabienne, Bathke, Barbara, Wennier, Sonia, Chaplin, Paul, Melero, Ignacio, Suter, Mark, Lauterbach, Henning, Berraondo, Pedro, Hochrein, Hubertus, Medina-Echeverz, José
Format: Artigo
Jezik:Inglês
Izdano: BMJ Publishing Group 2021
Teme:
Oncolytic and Local Immunotherapy
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7883866/
https://ncbi.nlm.nih.gov/pubmed/33579736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jitc-2020-001586
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki