Introduction of the Six Major Genomic Deletions of Modified Vaccinia Virus Ankara (MVA) into the Parental Vaccinia Virus Is Not Sufficient To Reproduce an MVA-Like Phenotype in Cell Culture and in Mice

Modified vaccinia virus Ankara (MVA) has a highly restricted host range in cell culture and is apathogenic in vivo. MVA was derived from the parental chorioallantois vaccinia virus Ankara (CVA) by more than 570 passages in chicken embryo fibroblast (CEF) cells. During CEF cell passaging, six major d...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Meisinger-Henschel, Christine, Späth, Michaela, Lukassen, Susanne, Wolferstätter, Michael, Kachelriess, Heike, Baur, Karen, Dirmeier, Ulrike, Wagner, Markus, Chaplin, Paul, Suter, Mark, Hausmann, Jürgen
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society for Microbiology (ASM) 2010
Θέματα:
Vaccines and Antiviral Agents
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2937755/
https://ncbi.nlm.nih.gov/pubmed/20668072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00756-10
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