Introduction of the Six Major Genomic Deletions of Modified Vaccinia Virus Ankara (MVA) into the Parental Vaccinia Virus Is Not Sufficient To Reproduce an MVA-Like Phenotype in Cell Culture and in Mice

Modified vaccinia virus Ankara (MVA) has a highly restricted host range in cell culture and is apathogenic in vivo. MVA was derived from the parental chorioallantois vaccinia virus Ankara (CVA) by more than 570 passages in chicken embryo fibroblast (CEF) cells. During CEF cell passaging, six major d...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Meisinger-Henschel, Christine, Späth, Michaela, Lukassen, Susanne, Wolferstätter, Michael, Kachelriess, Heike, Baur, Karen, Dirmeier, Ulrike, Wagner, Markus, Chaplin, Paul, Suter, Mark, Hausmann, Jürgen
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology (ASM) 2010
Pynciau:
Vaccines and Antiviral Agents
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2937755/
https://ncbi.nlm.nih.gov/pubmed/20668072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00756-10
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