Cardiac Safety of Modified Vaccinia Ankara for Vaccination against Smallpox in a Young, Healthy Study Population

BACKGROUND: Conventional smallpox vaccines based on replicating vaccinia virus (VV) strains (e.g. Lister Elstree, NYCBOH) are associated with a high incidence of myo-/pericarditis, a severe inflammatory cardiac complication. A new smallpox vaccine candidate based on a non-replicating Modified Vaccin...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Zitzmann-Roth, Eva-Maria, von Sonnenburg, Frank, de la Motte, Stephan, Arndtz-Wiedemann, Nathaly, von Krempelhuber, Alfred, Uebler, Nadine, Vollmar, Jens, Virgin, Garth, Chaplin, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4399887/
https://ncbi.nlm.nih.gov/pubmed/25879867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0122653
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