A Multicenter, Open-Label, Controlled Phase II Study to Evaluate Safety and Immunogenicity of MVA Smallpox Vaccine (IMVAMUNE) in 18–40 Year Old Subjects with Diagnosed Atopic Dermatitis

BACKGROUND: Replicating smallpox vaccines can cause severe complications in individuals with atopic dermatitis (AD). Prior studies evaluating Modified Vaccinia Ankara virus (MVA), a non-replicating vaccine in humans, showed a favorable safety and immunogenicity profile in healthy volunteers. OBJECTI...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Greenberg, Richard N, Hurley, Yadira, Dinh, Dinh V., Mraz, Serena, Vera, Javier Gomez, von Bredow, Dorothea, von Krempelhuber, Alfred, Roesch, Siegfried, Virgin, Garth, Arndtz-Wiedemann, Nathaly, Meyer, Thomas Peter, Schmidt, Darja, Nichols, Richard, Young, Philip, Chaplin, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4595076/
https://ncbi.nlm.nih.gov/pubmed/26439129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0138348
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