Survival of lethal poxvirus infection in mice depends on TLR9, and therapeutic vaccination provides protection

Poxviruses such as the causative agent of smallpox have developed multiple strategies to suppress immune responses, including the suppression of DC activation. Since poxviruses are large DNA viruses, we hypothesized that their detection by DCs may involve the endosomal DNA recognition receptor TLR9....

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Samuelsson, Christofer, Hausmann, Jürgen, Lauterbach, Henning, Schmidt, Michaela, Akira, Shizuo, Wagner, Hermann, Chaplin, Paul, Suter, Mark, O’Keeffe, Meredith, Hochrein, Hubertus
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Clinical Investigation 2008
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2289795/
https://ncbi.nlm.nih.gov/pubmed/18398511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI33940
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы