Herpes simplex virus type-1 induces IFN-α production via Toll-like receptor 9-dependent and -independent pathways

Type I IFN production in response to the DNA virus herpes simplex virus type-1 (HSV-1) is essential in controlling viral replication. We investigated whether plasmacytoid dendritic cells (pDC) were the major tissue source of IFN-α, and whether the production of IFN-α in response to HSV-1 depended on...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Hochrein, Hubertus, Schlatter, Beatrix, O'Keeffe, Meredith, Wagner, Cornelia, Schmitz, Frank, Schiemann, Matthias, Bauer, Stefan, Suter, Mark, Wagner, Hermann
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2004
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC509215/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15272082/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0403555101
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