Herpes simplex virus type-1 induces IFN-α production via Toll-like receptor 9-dependent and -independent pathways

Type I IFN production in response to the DNA virus herpes simplex virus type-1 (HSV-1) is essential in controlling viral replication. We investigated whether plasmacytoid dendritic cells (pDC) were the major tissue source of IFN-α, and whether the production of IFN-α in response to HSV-1 depended on...

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Autori principali: Hochrein, Hubertus, Schlatter, Beatrix, O'Keeffe, Meredith, Wagner, Cornelia, Schmitz, Frank, Schiemann, Matthias, Bauer, Stefan, Suter, Mark, Wagner, Hermann
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2004
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC509215/
https://ncbi.nlm.nih.gov/pubmed/15272082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0403555101
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