Coexpression of Interleukin-12 Chains by a Self-Splicing Vector Increases the Protective Cellular Immune Response of DNA and Mycobacterium bovis BCG Vaccines against Mycobacterium tuberculosis

More effective vaccines against Mycobacterium tuberculosis may contribute to the control of this major human pathogen. DNA vaccines encoding single mycobacterial proteins stimulate antimycobacterial T-cell responses and induce partial protection against M. tuberculosis in animal models. The protecti...

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Autori principali: Palendira, Umaimainthan, Kamath, Arun T., Feng, Carl G., Martin, Ela, Chaplin, Paul J., Triccas, James A., Britton, Warwick J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2002
Soggetti:
Microbial Immunity and Vaccines
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC127841/
https://ncbi.nlm.nih.gov/pubmed/11895958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.4.1949-1956.2002
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