Coexpression of Interleukin-12 Chains by a Self-Splicing Vector Increases the Protective Cellular Immune Response of DNA and Mycobacterium bovis BCG Vaccines against Mycobacterium tuberculosis

More effective vaccines against Mycobacterium tuberculosis may contribute to the control of this major human pathogen. DNA vaccines encoding single mycobacterial proteins stimulate antimycobacterial T-cell responses and induce partial protection against M. tuberculosis in animal models. The protecti...

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Bibliographische Detailangaben
Hauptverfasser: Palendira, Umaimainthan, Kamath, Arun T., Feng, Carl G., Martin, Ela, Chaplin, Paul J., Triccas, James A., Britton, Warwick J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2002
Schlagworte:
Microbial Immunity and Vaccines
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC127841/
https://ncbi.nlm.nih.gov/pubmed/11895958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.4.1949-1956.2002
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