Coexpression of Interleukin-12 Chains by a Self-Splicing Vector Increases the Protective Cellular Immune Response of DNA and Mycobacterium bovis BCG Vaccines against Mycobacterium tuberculosis

More effective vaccines against Mycobacterium tuberculosis may contribute to the control of this major human pathogen. DNA vaccines encoding single mycobacterial proteins stimulate antimycobacterial T-cell responses and induce partial protection against M. tuberculosis in animal models. The protecti...

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Dades bibliogràfiques

Publicat a:	Infect Immun
Autors principals:	Palendira, Umaimainthan, Kamath, Arun T., Feng, Carl G., Martin, Ela, Chaplin, Paul J., Triccas, James A., Britton, Warwick J.
Format:	Artigo
Idioma:	Inglês
Publicat:	American Society for Microbiology (ASM) 2002
Matèries:	Microbial Immunity and Vaccines
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC127841/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11895958/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.70.4.1949-1956.2002
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