Nascent connections: R-loops and chromatin patterning

Por Chédin, Frédéric
Publicado no Trends Genet (2016)

The DNA methyltransferase-like protein DNMT3L stimulates de novo methylation by Dnmt3a

Por Chédin, Frédéric, Lieber, Michael R., Hsieh, Chih-Lin
Publicado em 2002

Inactive DNMT3B Splice Variants Modulate De Novo DNA Methylation

Por Gordon, Catherine A., Hartono, Stella R., Chédin, Frédéric
Publicado em 2013

GC skew is a conserved property of unmethylated CpG island promoters across vertebrates

Por Hartono, Stella R., Korf, Ian F., Chédin, Frédéric
Publicado no Nucleic Acids Res (2015)

An Ultrasensitive High Throughput Screen for DNA Methyltransferase 1-Targeted Molecular Probes

Por Fagan, Rebecca L., Wu, Meng, Chédin, Frédéric, Brenner, Charles
Publicado em 2013

Transcription-Associated R-Loop Formation across the Human FMR1 CGG-Repeat Region

Por Loomis, Erick W., Sanz, Lionel A., Chédin, Frédéric, Hagerman, Paul J.
Publicado em 2014

UHRF1 Links the Histone code and DNA Methylation to ensure Faithful Epigenetic Memory Inheritance

Por Bronner, Christian, Fuhrmann, Guy, Chédin, Frédéric L, Macaluso, Marcella, Dhe-Paganon, Sirano
Publicado em 2010

R-loop formation is a distinctive characteristic of unmethylated human CpG island promoters

Por Ginno, Paul A., Lott, Paul L., Christensen, Holly C., Korf, Ian, Chédin, Frédéric
Publicado em 2012

GC skew at the 5′ and 3′ ends of human genes links R-loop formation to epigenetic regulation and transcription termination

Por Ginno, Paul A., Lim, Yoong Wearn, Lott, Paul L., Korf, Ian, Chédin, Frédéric
Publicado em 2013

Genome-wide DNA hypomethylation and RNA:DNA hybrid accumulation in Aicardi–Goutières syndrome

Por Lim, Yoong Wearn, Sanz, Lionel A, Xu, Xiaoqin, Hartono, Stella R, Chédin, Frédéric
Publicado no eLife (2015)

Arginine methylation facilitates the recruitment of TOP3B to chromatin to prevent R-loop accumulation

Por Yang, Yanzhong, McBride, Kevin M., Hensley, Sean, Lu, Yue, Chedin, Frederic, Bedford, Mark T.
Publicado em 2014

DNMT3L Modulates Significant and Distinct Flanking Sequence Preference for DNA Methylation by DNMT3A and DNMT3B In Vivo

Por Wienholz, Bethany L., Kareta, Michael S., Moarefi, Amir H., Gordon, Catherine A., Ginno, Paul A., Chédin, Frédéric
Publicado em 2010

Prevalent, dynamic, and conserved R-loop structures associate with specific epigenomic signatures in mammals

Por Sanz, Lionel A., Hartono, Stella R., Lim, Yoong Wearn, Steyaert, Sandra, Rajpurkar, Aparna, Ginno, Paul A., Xu, Xiaoqin, Chédin, Frédéric
Publicado no Mol Cell (2016)

Co-transcriptional R-loops are the main cause of estrogen-induced DNA damage

Por Stork, Caroline Townsend, Bocek, Michael, Crossley, Madzia P, Sollier, Julie, Sanz, Lionel A, Chédin, Frédéric, Swigut, Tomek, Cimprich, Karlene A
Publicado no eLife (2016)

Telomeres in ICF syndrome cells are vulnerable to DNA damage due to elevated DNA:RNA hybrids

Por Sagie, Shira, Toubiana, Shir, Hartono, Stella R., Katzir, Hagar, Tzur-Gilat, Aya, Havazelet, Shany, Francastel, Claire, Velasco, Guillaume, Chédin, Frédéric, Selig, Sara
Publicado no Nat Commun (2017)

R-loop formation at Snord116 mediates topotecan inhibition of Ube3a-antisense and allele-specific chromatin decondensation

Por Powell, Weston T., Coulson, Rochelle L., Gonzales, Michael L., Crary, Florence K., Wong, Spencer S., Adams, Sarrita, Ach, Robert A., Tsang, Peter, Yamada, Nazumi Alice, Yasui, Dag H., Chédin, Frédéric, LaSalle, Janine M.
Publicado em 2013

Recognition of Multivalent Histone States Associated with Heterochromatin by UHRF1 Protein

Por Nady, Nataliya, Lemak, Alexander, Walker, John R., Avvakumov, George V., Kareta, Michael S., Achour, Mayada, Xue, Sheng, Duan, Shili, Allali-Hassani, Abdellah, Zuo, Xiaobing, Wang, Yun-Xing, Bronner, Christian, Chédin, Frédéric, Arrowsmith, Cheryl H., Dhe-Paganon, Sirano
Publicado em 2011