Recognition of Multivalent Histone States Associated with Heterochromatin by UHRF1 Protein

Histone modifications and DNA methylation represent two layers of heritable epigenetic information that regulate eukaryotic chromatin structure and gene activity. UHRF1 is a unique factor that bridges these two layers; it is required for maintenance DNA methylation at hemimethylated CpG sites, which...

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Detalhes bibliográficos
Main Authors: Nady, Nataliya, Lemak, Alexander, Walker, John R., Avvakumov, George V., Kareta, Michael S., Achour, Mayada, Xue, Sheng, Duan, Shili, Allali-Hassani, Abdellah, Zuo, Xiaobing, Wang, Yun-Xing, Bronner, Christian, Chédin, Frédéric, Arrowsmith, Cheryl H., Dhe-Paganon, Sirano
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Molecular Biophysics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3129210/
https://ncbi.nlm.nih.gov/pubmed/21489993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.234104
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