Recognition of Multivalent Histone States Associated with Heterochromatin by UHRF1 Protein

Histone modifications and DNA methylation represent two layers of heritable epigenetic information that regulate eukaryotic chromatin structure and gene activity. UHRF1 is a unique factor that bridges these two layers; it is required for maintenance DNA methylation at hemimethylated CpG sites, which...

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Détails bibliographiques
Auteurs principaux: Nady, Nataliya, Lemak, Alexander, Walker, John R., Avvakumov, George V., Kareta, Michael S., Achour, Mayada, Xue, Sheng, Duan, Shili, Allali-Hassani, Abdellah, Zuo, Xiaobing, Wang, Yun-Xing, Bronner, Christian, Chédin, Frédéric, Arrowsmith, Cheryl H., Dhe-Paganon, Sirano
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2011
Sujets:
Molecular Biophysics
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3129210/
https://ncbi.nlm.nih.gov/pubmed/21489993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.234104
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