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Arginine methylation facilitates the recruitment of TOP3B to chromatin to prevent R-loop accumulation
Tudor domain containing protein 3 (TDRD3) is a major methyl-arginine effector molecule that “reads” methyl-histone marks and facilitates gene transcription. However, the underlying mechanism by which TDRD3 functions as a transcriptional coactivator is unknown. We identified topoisomerase IIIB (TOP3B...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3959860/ https://ncbi.nlm.nih.gov/pubmed/24507716 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2014.01.011 |
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