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Arginine methylation of the C-terminus RGG motif promotes TOP3B topoisomerase activity and stress granule localization
DNA topoisomerase 3B (TOP3B) is unique among all mammalian topoisomerases for its dual activities that resolve both DNA and RNA topological entanglements to facilitate transcription and translation. However, the mechanism by which TOP3B activity is regulated is still elusive. Here, we have identifie...
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| Publicado no: | Nucleic Acids Res |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5888246/ https://ncbi.nlm.nih.gov/pubmed/29471495 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky103 |
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