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Arginine methylation of the C-terminus RGG motif promotes TOP3B topoisomerase activity and stress granule localization
DNA topoisomerase 3B (TOP3B) is unique among all mammalian topoisomerases for its dual activities that resolve both DNA and RNA topological entanglements to facilitate transcription and translation. However, the mechanism by which TOP3B activity is regulated is still elusive. Here, we have identifie...
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| Udgivet i: | Nucleic Acids Res |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5888246/ https://ncbi.nlm.nih.gov/pubmed/29471495 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky103 |
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