The non-RNase H domain of Saccharomyces cerevisiae RNase H1 binds double-stranded RNA: magnesium modulates the switch between double-stranded RNA binding and RNase H activity.

av Cerritelli, S M, Crouch, R J
Publicerad 1995

Ribonuclease H: the enzymes in Eukaryotes

av Cerritelli, Susana M., Crouch, Robert J.
Publicerad 2008

The Balancing Act of Ribonucleotides in DNA

av Cerritelli, Susana M., Crouch, Robert J.
I publikationen Trends Biochem Sci (2016)

RNase H2-RED carpets the path to eukaryotic RNase H2 functions

av Cerritelli, Susana M., Crouch, Robert J.
I publikationen DNA Repair (Amst) (2019)

RNases H: Multiple roles in maintaining genome integrity

av Cerritelli, Susana M., Crouch, Robert J.
I publikationen DNA Repair (Amst) (2019)

A New Twist for Topisomerase 1: “Topoisomerase creates 2–5 base pair deletions by attacking ribonucleotides in DNA”

av Cerritelli, Susana M., Chon, Hyongi, Crouch, Robert J.
Publicerad 2011

A common 40 amino acid motif in eukaryotic RNases H1 and caulimovirus ORF VI proteins binds to duplex RNAs.

av Cerritelli, S M, Fedoroff, O Y, Reid, B R, Crouch, R J
Publicerad 1998

The Structural and Biochemical Characterization of Human RNase H2 Complex Reveals the Molecular Basis for Substrate Recognition and Aicardi-Goutières Syndrome Defects

av Figiel, Małgorzata, Chon, Hyongi, Cerritelli, Susana M., Cybulska, Magdalena, Crouch, Robert J., Nowotny, Marcin
Publicerad 2011

Quantitative Regulation of Class Switch Recombination by Switch Region Transcription

av Lee, Chung-Gi, Kinoshita, Kazuo, Arudchandran, Arulvathani, Cerritelli, Susana M., Crouch, Robert J., Honjo, Tasuku
Publicerad 2001

Specific recognition of RNA/DNA hybrid and enhancement of human RNase H1 activity by HBD

av Nowotny, Marcin, Cerritelli, Susana M, Ghirlando, Rodolfo, Gaidamakov, Sergei A, Crouch, Robert J, Yang, Wei
Publicerad 2008

Crystal Structures of RNase H2 in Complex with Nucleic Acid Reveal the Mechanism of RNA-DNA Junction Recognition and Cleavage

av Rychlik, Monika P., Chon, Hyongi, Cerritelli, Susana M., Klimek, Paulina, Crouch, Robert J., Nowotny, Marcin
Publicerad 2010

Unlocking the steric gate of DNA polymerase η leads to increased genomic instability in Saccharomyces cerevisiae

av Donigan, Katherine A., Cerritelli, Susana M., McDonald, John P., Vaisman, Alexandra, Crouch, Robert J., Woodgate, Roger
I publikationen DNA Repair (Amst) (2015)

High density of unrepaired genomic ribonucleotides leads to Topoisomerase 1-mediated severe growth defects in absence of ribonucleotide reductase

av Cerritelli, Susana M, Iranzo, Jaime, Sharma, Sushma, Chabes, Andrei, Crouch, Robert J, Tollervey, David, El Hage, Aziz
I publikationen Nucleic Acids Res (2020)

An Upstream Open Reading Frame and the Context of the Two AUG Codons Affect the Abundance of Mitochondrial and Nuclear RNase H1

av Suzuki, Yutaka, Holmes, J. Bradley, Cerritelli, Susana M., Sakhuja, Kiran, Minczuk, Michal, Holt, Ian J., Crouch, Robert J.
Publicerad 2010

RNase H2 roles in genome integrity revealed by unlinking its activities

av Chon, Hyongi, Sparks, Justin L., Rychlik, Monika, Nowotny, Marcin, Burgers, Peter M., Crouch, Robert J., Cerritelli, Susana M.
Publicerad 2013

Eukaryotic RNases H1 act processively by interactions through the duplex RNA-binding domain

av Gaidamakov, Sergei A., Gorshkova, Inna I., Schuck, Peter, Steinbach, Peter J., Yamada, Hirofumi, Crouch, Robert J., Cerritelli, Susana M.
Publicerad 2005

RNase H2-Initiated Ribonucleotide Excision Repair

av Sparks, Justin L., Chon, Hyongi, Cerritelli, Susana M., Kunkel, Thomas A., Johansson, Erik, Crouch, Robert J., Burgers, Peter M.
Publicerad 2012

R-loop depletion by over expressed RNase H1 in mouse B cells increases activation-induced deaminase access to the transcribed strand without altering frequency of isotype switching

av Maul, Robert W., Chon, Hyongi, Sakhuja, Kiran, Cerritelli, Susana M., Gugliotti, Lina A., Gearhart, Patricia J., Crouch, Robert J.
I publikationen J Mol Biol (2017)

Two RNase H2 Mutants with Differential rNMP Processing Activity Reveal a Threshold of Ribonucleotide Tolerance for Embryonic Development

av Uehara, Ryo, Cerritelli, Susana M., Hasin, Naushaba, Sakhuja, Kiran, London, Mariya, Iranzo, Jaime, Chon, Hyongi, Grinberg, Alexander, Crouch, Robert J.
I publikationen Cell Rep (2018)

Contributions of the two accessory subunits, RNASEH2B and RNASEH2C, to the activity and properties of the human RNase H2 complex

av Chon, Hyongi, Vassilev, Alex, DePamphilis, Melvin L., Zhao, Yingming, Zhang, Junmei, Burgers, Peter M., Crouch, Robert J., Cerritelli, Susana M.
Publicerad 2009