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Unlocking the steric gate of DNA polymerase η leads to increased genomic instability in Saccharomyces cerevisiae
DNA polymerase η (pol η) is best characterized for its ability to perform accurate and efficient translesion DNA synthesis (TLS) through cyclobutane pyrimidine dimers (CPDs). To ensure accurate bypass the polymerase is not only required to select the correct base, but also discriminate between NTPs...
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| 出版年: | DNA Repair (Amst) |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4651834/ https://ncbi.nlm.nih.gov/pubmed/26340535 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2015.07.002 |
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