The Steric Gate of DNA Polymerase ι Regulates Ribonucleotide Incorporation and Deoxyribonucleotide Fidelity

Accurate DNA synthesis in vivo depends on the ability of DNA polymerases to select dNTPs from a nucleotide pool dominated by NTPs. High fidelity replicative polymerases have evolved to efficiently exclude NTPs while copying long stretches of undamaged DNA. However, to bypass DNA damage, cells utiliz...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Donigan, Katherine A., McLenigan, Mary P., Yang, Wei, Goodman, Myron F., Woodgate, Roger
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2014
Matèries:
Enzymology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3979402/
https://ncbi.nlm.nih.gov/pubmed/24532793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.545442
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars