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DNA polymerase ι is acetylated in response to S(N)2 alkylating agents

DNA polymerase iota (Polι) belongs to the Y-family of DNA polymerases that are involved in DNA damage tolerance through their role in translesion DNA synthesis. Like all other Y-family polymerases, Polι interacts with proliferating cell nuclear antigen (PCNA), Rev1, ubiquitin and ubiquitinated-PCNA...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: McIntyre, Justyna, Sobolewska, Aleksandra, Fedorowicz, Mikolaj, McLenigan, Mary P., Macias, Matylda, Woodgate, Roger, Sledziewska-Gojska, Ewa
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6423139/
https://ncbi.nlm.nih.gov/pubmed/30886224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-41249-3
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