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Eukaryotic RNases H1 act processively by interactions through the duplex RNA-binding domain
Ribonucleases H have mostly been implicated in eliminating short RNA primers used for initiation of lagging strand DNA synthesis. Escherichia coli RNase HI cleaves these RNA–DNA hybrids in a distributive manner. We report here that eukaryotic RNases H1 have evolved to be processive enzymes by attach...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1079969/ https://ncbi.nlm.nih.gov/pubmed/15831789 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki510 |
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