Contributions of the two accessory subunits, RNASEH2B and RNASEH2C, to the activity and properties of the human RNase H2 complex

Eukaryotic RNase H2 is a heterotrimeric enzyme. Here, we show that the biochemical composition and stoichiometry of the human RNase H2 complex is consistent with the properties previously deduced from genetic studies. The catalytic subunit of eukaryotic RNase H2, RNASEH2A, is well conserved and simi...

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Detalhes bibliográficos
Main Authors: Chon, Hyongi, Vassilev, Alex, DePamphilis, Melvin L., Zhao, Yingming, Zhang, Junmei, Burgers, Peter M., Crouch, Robert J., Cerritelli, Susana M.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2009
Assuntos:
Nucleic Acid Enzymes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2615623/
https://ncbi.nlm.nih.gov/pubmed/19015152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn913
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