Thyroid Cancer: Role of RET and Beyond

by Carlomagno, Francesca
Published 2012

Oncogenic rearrangements driving ionizing radiation–associated human cancer

by Santoro, Massimo, Carlomagno, Francesca
Published 2013

Central Role of RET in Thyroid Cancer

by Santoro, Massimo, Carlomagno, Francesca
Published 2013

RET Gene Fusions in Malignancies of the Thyroid and Other Tissues

by Santoro, Massimo, Moccia, Marialuisa, Federico, Giorgia, Carlomagno, Francesca
Published in Genes (Basel) (2020)

Mutations in the Extracellular Domain Cause RET Loss of Function by a Dominant Negative Mechanism

by Cosma, Maria Pia, Cardone, Monica, Carlomagno, Francesca, Colantuoni, Vittorio
Published 1998

The molecular basis for RET tyrosine-kinase inhibitors in thyroid cancer

by De Falco, Valentina, Carlomagno, Francesca, Li, Hong-yu, Santoro, Massimo
Published in Best Pract Res Clin Endocrinol Metab (2017)

Identification of two novel RET kinase inhibitors through MCR-based drug discovery: Design, synthesis and evaluation

by Frett, Brendan, Moccia, Marialuisa, Carlomagno, Francesca, Santoro, Massimo, Li, Hong-yu
Published in Eur J Med Chem (2014)

Tamoxifen erythroid toxicity revealed by studying the role of nuclear receptor co-activator 4 in erythropoiesis

by Nai, Antonella, Pettinato, Mariateresa, Federico, Giorgia, Olivari, Violante, Carlomagno, Francesca, Silvestri, Laura
Published in Haematologica (2019)

Structure Prediction and Validation of the ERK8 Kinase Domain

by Strambi, Angela, Mori, Mattia, Rossi, Matteo, Colecchia, David, Manetti, Fabrizio, Carlomagno, Francesca, Botta, Maurizio, Chiariello, Mario
Published 2013

Molecular Mechanism of 17-Allylamino-17-demethoxygeldanamycin (17-AAG)-induced AXL Receptor Tyrosine Kinase Degradation

by Krishnamoorthy, Gnana Prakasam, Guida, Teresa, Alfano, Luigi, Avilla, Elvira, Santoro, Massimo, Carlomagno, Francesca, Melillo, Rosa Marina
Published 2013

Insights into Current Tropomyosin Receptor Kinase (TRK) Inhibitors: Development and Clinical Application

by Yan, Wei, Lakkaniga, Naga Rajiv, Carlomagno, Francesca, Santoro, Massimo, McDonald, Neil Q., Lv, Fengping, Gunaganti, Naresh, Frett, Brendan, Li, Hong-yu
Published in J Med Chem (2018)

NCOA4-mediated ferritinophagy in macrophages is crucial to sustain erythropoiesis in mice

by Nai, Antonella, Lidonnici, Maria Rosa, Federico, Giorgia, Pettinato, Mariateresa, Olivari, Violante, Carrillo, Federica, Crich, Simonetta Geninatti, Ferrari, Giuliana, Camaschella, Clara, Silvestri, Laura, Carlomagno, Francesca
Published in Haematologica (2020)

The Oncogenic Activity of RET Point Mutants for Follicular Thyroid Cells May Account for the Occurrence of Papillary Thyroid Carcinoma in Patients Affected by Familial Medullary Th...

by Melillo, Rosa Marina, Cirafici, Anna Maria, De Falco, Valentina, Bellantoni, Marie, Chiappetta, Gennaro, Fusco, Alfredo, Carlomagno, Francesca, Picascia, Antonella, Tramontano, Donatella, Tallini, Giovanni, Santoro, Massimo
Published 2004

Fragment-based discovery of a dual pan-RET/VEGFR2 kinase inhibitor optimized for single-agent polypharmacology()

by Frett, Brendan, Carlomagno, Francesca, Moccia, Maria Luisa, Brescia, Annalisa, Federico, Giorgia, De Falco, Valentina, Admire, Brittany, Chen, Zhongzhu, Qi, Wenqing, Santoro, Massimo, Li, Hong-yu
Published in Angew Chem Int Ed Engl (2015)

Potent Mitogenicity of the RET/PTC3 Oncogene Correlates with Its Prevalence in Tall-Cell Variant of Papillary Thyroid Carcinoma

by Basolo, Fulvio, Giannini, Riccardo, Monaco, Carmen, Melillo, Rosa Marina, Carlomagno, Francesca, Pancrazi, Martina, Salvatore, Giuliana, Chiappetta, Gennaro, Pacini, Furio, Elisei, Rossella, Miccoli, Paolo, Pinchera, Aldo, Fusco, Alfredo, Santoro, Massimo
Published 2002

Identification of Novel Small Molecule Inhibitors of Oncogenic RET Kinase

by Moccia, Marialuisa, Liu, Qingsong, Guida, Teresa, Federico, Giorgia, Brescia, Annalisa, Zhao, Zheng, Choi, Hwan Geun, Deng, Xianming, Tan, Li, Wang, Jinhua, Billaud, Marc, Gray, Nathanael S., Carlomagno, Francesca, Santoro, Massimo
Published in PLoS One (2015)

Functional characterization of a novel FGFR1OP‐RET rearrangement in hematopoietic malignancies

by Bossi, Daniela, Carlomagno, Francesca, Pallavicini, Isabella, Pruneri, Giancarlo, Trubia, Maurizio, Raviele, Paola Rafaniello, Marinelli, Alessandra, Anaganti, Suresh, Cox, Maria Christina, Viale, Giuseppe, Santoro, Massimo, Di Fiore, Pier Paolo, Minucci, Saverio
Published in Mol Oncol (2013)

Bioisosteric Discovery of NPA101.3, a Second-Generation RET/VEGFR2 Inhibitor Optimized for Single-Agent Polypharmacology

by Moccia, Marialuisa, Frett, Brendan, Zhang, Lingtian, Lakkaniga, Naga Rajiv, Briggs, David C., Chauhan, Rakhee, Brescia, Annalisa, Federico, Giorgia, Yan, Wei, Santoro, Massimo, McDonald, Neil Q., Li, Hong-yu, Carlomagno, Francesca
Published in J Med Chem (2020)

Iron and Ferritin Modulate MHC Class I Expression and NK Cell Recognition

by Sottile, Rosa, Federico, Giorgia, Garofalo, Cinzia, Tallerico, Rossana, Faniello, Maria Concetta, Quaresima, Barbara, Cristiani, Costanza Maria, Di Sanzo, Maddalena, Cuda, Gianni, Ventura, Valeria, Wagner, Arnika Kathleen, Contrò, Gianluca, Perrotti, Nicola, Gulletta, Elio, Ferrone, Soldano, Kärre, Klas, Costanzo, Francesco Saverio, Carlomagno, Francesca, Carbone, Ennio
Published in Front Immunol (2019)

The Extent of Linkage Disequilibrium in Four Populations with Distinct Demographic Histories

by Dunning, Alison M., Durocher, Francine, Healey, Catherine S., Teare, M. Dawn, McBride, Simon E., Carlomagno, Francesca, Xu, Chun-Fang, Dawson, Elisabeth, Rhodes, Susan, Ueda, Saeko, Lai, Eric, Luben, Robert N., Van Rensburg, Elizabeth J., Mannermaa, Arto, Kataja, Vesa, Rennart, Gadi, Dunham, Ian, Purvis, Ian, Easton, Douglas, Ponder, Bruce A. J.
Published 2000