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Structure Prediction and Validation of the ERK8 Kinase Domain
Extracellular signal-regulated kinase 8 (ERK8) has been already implicated in cell transformation and in the protection of genomic integrity and, therefore, proposed as a novel potential therapeutic target for cancer. In the absence of a crystal structure, we developed a three-dimensional model for...
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| Hauptverfasser: | , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3543423/ https://ncbi.nlm.nih.gov/pubmed/23326322 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0052011 |
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