Multiple Mitogen-Activated Protein Kinase Signaling Pathways Connect the Cot Oncoprotein to the c-jun Promoter and to Cellular Transformation

by Chiariello, Mario, Marinissen, Maria Julia, Gutkind, J. Silvio
Published 2000

Regulation of gene expression by the small GTPase Rho through the ERK6 (p38γ) MAP kinase pathway

by Marinissen, Maria Julia, Chiariello, Mario, Gutkind, J. Silvio
Published 2001

A Network of Mitogen-Activated Protein Kinases Links G Protein-Coupled Receptors to the c-jun Promoter: a Role for c-Jun NH(2)-Terminal Kinase, p38s, and Extracellular Signal-Re...

by Marinissen, Maria Julia, Chiariello, Mario, Pallante, Michael, Gutkind, J. Silvio
Published 1999

MAPK15 is part of the ULK complex and controls its activity to regulate early phases of the autophagic process

by Colecchia, David, Dapporto, Francesca, Tronnolone, Serena, Salvini, Laura, Chiariello, Mario
Published in J Biol Chem (2018)

Activated kinase screening identifies the IKBKE oncogene as a positive regulator of autophagy

by Leonardi, Margherita, Perna, Eluisa, Tronnolone, Serena, Colecchia, David, Chiariello, Mario
Published in Autophagy (2018)

MAPK15 mediates BCR-ABL1-induced autophagy and regulates oncogene-dependent cell proliferation and tumor formation

by Colecchia, David, Rossi, Matteo, Sasdelli, Federica, Sanzone, Sveva, Strambi, Angela, Chiariello, Mario
Published in Autophagy (2015)

RAB7A Regulates Vimentin Phosphorylation through AKT and PAK

by Romano, Roberta, Calcagnile, Matteo, Margiotta, Azzurra, Franci, Lorenzo, Chiariello, Mario, Alifano, Pietro, Bucci, Cecilia
Published in Cancers (Basel) (2021)

Extracellular Signal-regulated Kinase 8 (ERK8) Controls Estrogen-related Receptor α (ERRα) Cellular Localization and Inhibits Its Transcriptional Activity

by Rossi, Matteo, Colecchia, David, Iavarone, Carlo, Strambi, Angela, Piccioni, Federica, Verrotti di Pianella, Arturo, Chiariello, Mario
Published 2011

Structure Prediction and Validation of the ERK8 Kinase Domain

by Strambi, Angela, Mori, Mattia, Rossi, Matteo, Colecchia, David, Manetti, Fabrizio, Carlomagno, Francesca, Botta, Maurizio, Chiariello, Mario
Published 2013

Aptamer targeting EGFRvIII mutant hampers its constitutive autophosphorylation and affects migration, invasion and proliferation of glioblastoma cells

by Camorani, Simona, Crescenzi, Elvira, Colecchia, David, Carpentieri, Andrea, Amoresano, Angela, Fedele, Monica, Chiariello, Mario, Cerchia, Laura
Published in Oncotarget (2015)

Plasmin-Binding Tripeptide-Decorated Liposomes Loading Pyrazolo[3,4-d]pyrimidines for Targeting Hepatocellular Carcinoma

by Calandro, Pierpaolo, Iovenitti, Giulia, Zamperini, Claudio, Candita, Francesca, Dreassi, Elena, Chiariello, Mario, Angelucci, Adriano, Schenone, Silvia, Botta, Maurizio, Mancini, Arianna
Published in ACS Med Chem Lett (2018)

MAPK15/ERK8 stimulates autophagy by interacting with LC3 and GABARAP proteins

by Colecchia, David, Strambi, Angela, Sanzone, Sveva, Iavarone, Carlo, Rossi, Matteo, Dall’Armi, Claudia, Piccioni, Federica, Verrotti di Pianella, Arturo, Chiariello, Mario
Published 2012

Cross-talk between MET and EGFR in non-small cell lung cancer involves miR-27a and Sprouty2

by Acunzo, Mario, Romano, Giulia, Palmieri, Dario, Laganá, Alessandro, Garofalo, Michela, Balatti, Veronica, Drusco, Alessandra, Chiariello, Mario, Nana-Sinkam, Patrick, Croce, Carlo M.
Published 2013

Alterations of autophagy in the peripheral neuropathy Charcot-Marie-Tooth type 2B

by Colecchia, David, Stasi, Mariangela, Leonardi, Margherita, Manganelli, Fiore, Nolano, Maria, Veneziani, Bianca Maria, Santoro, Lucio, Eskelinen, Eeva-Liisa, Chiariello, Mario, Bucci, Cecilia
Published in Autophagy (2018)

MAPK15 upregulation promotes cell proliferation and prevents DNA damage in male germ cell tumors

by Rossi, Matteo, Colecchia, David, Ilardi, Gennaro, Acunzo, Mario, Nigita, Giovanni, Sasdelli, Federica, Celetti, Angela, Strambi, Angela, Staibano, Stefania, Croce, Carlo Maria, Chiariello, Mario
Published in Oncotarget (2016)

Improvement of pyrazolo[3,4-d]pyrimidines pharmacokinetic properties: nanosystem approaches for drug delivery

by Vignaroli, Giulia, Calandro, Pierpaolo, Zamperini, Claudio, Coniglio, Federica, Iovenitti, Giulia, Tavanti, Matteo, Colecchia, David, Dreassi, Elena, Valoti, Massimo, Schenone, Silvia, Chiariello, Mario, Botta, Maurizio
Published in Sci Rep (2016)

Targeted inhibition of Hedgehog-GLI signaling by novel acylguanidine derivatives inhibits melanoma cell growth by inducing replication stress and mitotic catastrophe

by Pietrobono, Silvia, Santini, Roberta, Gagliardi, Sinforosa, Dapporto, Francesca, Colecchia, David, Chiariello, Mario, Leone, Cosima, Valoti, Massimo, Manetti, Fabrizio, Petricci, Elena, Taddei, Maurizio, Stecca, Barbara
Published in Cell Death Dis (2018)

miR-130a targets MET and induces TRAIL-sensitivity in NSCLC by downregulating miR-221&222

by Acunzo, Mario, Visone, Rosa, Romano, Giulia, Veronese, Angelo, Lovat, Francesca, Palmieri, Dario, Bottoni, Arianna, Garofalo, Michela, Gasparini, Pierluigi, Condorelli, Gerolama, Chiariello, Mario, Croce, Carlo Maria
Published 2011

Superior Properties of N-Acetylcysteine Ethyl Ester over N-Acetyl Cysteine to Prevent Retinal Pigment Epithelial Cells Oxidative Damage

by Tosi, Gian Marco, Giustarini, Daniela, Franci, Lorenzo, Minetti, Alberto, Imperatore, Francesco, Caldi, Elena, Fiorenzani, Paolo, Aloisi, Anna Maria, Sparatore, Anna, Rossi, Ranieri, Chiariello, Mario, Orlandini, Maurizio, Galvagni, Federico
Published in Int J Mol Sci (2021)

EGFR-Targeted Magnetic Nanovectors Recognize, in Vivo, Head and Neck Squamous Cells Carcinoma-Derived Tumors

by Colecchia, David, Nicolato, Elena, Ravagli, Costanza, Faraoni, Paola, Strambi, Angela, Rossi, Matteo, Doumett, Saer, Mosconi, Elisa, Locatelli, Erica, Comes Franchini, Mauro, Balzi, Manuela, Baldi, Giovanni, Marzola, Pasquina, Chiariello, Mario
Published in ACS Med Chem Lett (2017)