MAPK15 mediates BCR-ABL1-induced autophagy and regulates oncogene-dependent cell proliferation and tumor formation

A reciprocal translocation of the ABL1 gene to the BCR gene results in the expression of the oncogenic BCR-ABL1 fusion protein, which characterizes human chronic myeloid leukemia (CML), a myeloproliferative disorder considered invariably fatal until the introduction of the imatinib family of tyrosin...

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書目詳細資料
發表在:Autophagy
Main Authors: Colecchia, David, Rossi, Matteo, Sasdelli, Federica, Sanzone, Sveva, Strambi, Angela, Chiariello, Mario
格式: Artigo
語言:Inglês
出版: Taylor & Francis 2015
主題:
Basic Research Papers
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4824572/
https://ncbi.nlm.nih.gov/pubmed/26291129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2015.1084454
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