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The N-Terminal Domain of ERK1 Accounts for the Functional Differences with ERK2

The Extracellular Regulated Kinase 1 and 2 transduce a variety of extracellular stimuli regulating processes as diverse as proliferation, differentiation and synaptic plasticity. Once activated in the cytoplasm, ERK1 and ERK2 translocate into the nucleus and interact with nuclear substrates to induc...

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Библиографические подробности
Главные авторы: Marchi, Matilde, D'Antoni, Angela, Formentini, Ivan, Parra, Riccardo, Brambilla, Riccardo, Ratto, Gian Michele, Costa, Mario
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2008
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2585810/
https://ncbi.nlm.nih.gov/pubmed/19052640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0003873
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