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The N-Terminal Domain of ERK1 Accounts for the Functional Differences with ERK2

The Extracellular Regulated Kinase 1 and 2 transduce a variety of extracellular stimuli regulating processes as diverse as proliferation, differentiation and synaptic plasticity. Once activated in the cytoplasm, ERK1 and ERK2 translocate into the nucleus and interact with nuclear substrates to induc...

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Detalhes bibliográficos
Main Authors: Marchi, Matilde, D'Antoni, Angela, Formentini, Ivan, Parra, Riccardo, Brambilla, Riccardo, Ratto, Gian Michele, Costa, Mario
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2585810/
https://ncbi.nlm.nih.gov/pubmed/19052640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0003873
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