Extracellular Signal-regulated Kinase 8 (ERK8) Controls Estrogen-related Receptor α (ERRα) Cellular Localization and Inhibits Its Transcriptional Activity

ERK8 (MAPK15) is a large MAP kinase already implicated in the regulation of the functions of different nuclear receptors and in cellular proliferation and transformation. Here, we identify ERRα as a novel ERK8-interacting protein. As a consequence of such interaction, ERK8 induces CRM1-dependent tra...

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Autors principals: Rossi, Matteo, Colecchia, David, Iavarone, Carlo, Strambi, Angela, Piccioni, Federica, Verrotti di Pianella, Arturo, Chiariello, Mario
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2011
Matèries:
Signal Transduction
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3048734/
https://ncbi.nlm.nih.gov/pubmed/21190936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.179523
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