Potent Mitogenicity of the RET/PTC3 Oncogene Correlates with Its Prevalence in Tall-Cell Variant of Papillary Thyroid Carcinoma

The tall-cell variant (TCV) of papillary thyroid carcinoma (PTC), characterized by tall cells bearing an oxyphilic cytoplasm, is more clinically aggressive than conventional PTC. RET tyrosine kinase rearrangements, which represent the most frequent genetic alteration in PTC, lead to the recombinatio...

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Detalhes bibliográficos
Main Authors: Basolo, Fulvio, Giannini, Riccardo, Monaco, Carmen, Melillo, Rosa Marina, Carlomagno, Francesca, Pancrazi, Martina, Salvatore, Giuliana, Chiappetta, Gennaro, Pacini, Furio, Elisei, Rossella, Miccoli, Paolo, Pinchera, Aldo, Fusco, Alfredo, Santoro, Massimo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2002
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1867131/
https://ncbi.nlm.nih.gov/pubmed/11786418
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