Potent Mitogenicity of the RET/PTC3 Oncogene Correlates with Its Prevalence in Tall-Cell Variant of Papillary Thyroid Carcinoma

The tall-cell variant (TCV) of papillary thyroid carcinoma (PTC), characterized by tall cells bearing an oxyphilic cytoplasm, is more clinically aggressive than conventional PTC. RET tyrosine kinase rearrangements, which represent the most frequent genetic alteration in PTC, lead to the recombinatio...

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Bibliographische Detailangaben
Hauptverfasser: Basolo, Fulvio, Giannini, Riccardo, Monaco, Carmen, Melillo, Rosa Marina, Carlomagno, Francesca, Pancrazi, Martina, Salvatore, Giuliana, Chiappetta, Gennaro, Pacini, Furio, Elisei, Rossella, Miccoli, Paolo, Pinchera, Aldo, Fusco, Alfredo, Santoro, Massimo
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Investigative Pathology 2002
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Regular Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1867131/
https://ncbi.nlm.nih.gov/pubmed/11786418
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