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NCOA4-mediated ferritinophagy in macrophages is crucial to sustain erythropoiesis in mice
Nuclear receptor coactivator 4 (NCOA4) promotes ferritin degradation and Ncoa4-ko mice in a C57BL/6 background show microcytosis and mild anemia, aggravated by iron deficiency. To understand tissue-specific contributions of NCOA4-mediated ferritinophagy we explored the effect of Ncoa4 genetic ablati...
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| Publicado no: | Haematologica |
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| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Fondazione Ferrata Storti
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7928015/ https://ncbi.nlm.nih.gov/pubmed/32107334 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2019.241232 |
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