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Transferrin receptor 2 is a potential novel therapeutic target for β-thalassemia: evidence from a murine model

β-thalassemias are genetic disorders characterized by anemia, ineffective erythropoiesis, and iron overload. Current treatment of severe cases is based on blood transfusion and iron chelation or allogeneic bone marrow (BM) transplantation. Novel approaches are explored for nontransfusion-dependent p...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Blood
Hauptverfasser: Artuso, Irene, Lidonnici, Maria Rosa, Altamura, Sandro, Mandelli, Giacomo, Pettinato, Mariateresa, Muckenthaler, Martina U., Silvestri, Laura, Ferrari, Giuliana, Camaschella, Clara, Nai, Antonella
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Hematology 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6302281/
https://ncbi.nlm.nih.gov/pubmed/30209118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2018-05-852277
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