Transferrin receptor 2 is a potential novel therapeutic target for β-thalassemia: evidence from a murine model

β-thalassemias are genetic disorders characterized by anemia, ineffective erythropoiesis, and iron overload. Current treatment of severe cases is based on blood transfusion and iron chelation or allogeneic bone marrow (BM) transplantation. Novel approaches are explored for nontransfusion-dependent p...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Artuso, Irene, Lidonnici, Maria Rosa, Altamura, Sandro, Mandelli, Giacomo, Pettinato, Mariateresa, Muckenthaler, Martina U., Silvestri, Laura, Ferrari, Giuliana, Camaschella, Clara, Nai, Antonella
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2018
Assuntos:
Red Cells, Iron, and Erythropoiesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6302281/
https://ncbi.nlm.nih.gov/pubmed/30209118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2018-05-852277
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