A dynamical systems model of progesterone receptor interactions with inflammation in human parturition

著者: Brubaker, Douglas, Barbaro, Alethea, R. Chance, Mark, Mesiano, Sam
出版年 BMC Syst Biol (2016)

FREQUENT SUBGRAPH MINING OF PERSONALIZED SIGNALING PATHWAY NETWORKS GROUPS PATIENTS WITH FREQUENTLY DYSREGULATED DISEASE PATHWAYS AND PREDICTS PROGNOSIS

著者: Durmaz, Arda, Henderson, Tim A. D., Brubaker, Douglas, Bebek, Gurkan
出版年 Pac Symp Biocomput (2017)

Computational translation of genomic responses from experimental model systems to humans

著者: Brubaker, Douglas K., Proctor, Elizabeth A., Haigis, Kevin M., Lauffenburger, Douglas A.
出版年 PLoS Comput Biol (2019)

Clostridioides difficile-Associated Antibiotics Alter Human Mucosal Barrier Functions by Microbiome-Independent Mechanisms

著者: Kester, Jemila C., Brubaker, Douglas K., Velazquez, Jason, Wright, Charles, Lauffenburger, Douglas A., Griffith, Linda G.
出版年 Antimicrob Agents Chemother (2020)

DRUG INTERVENTION RESPONSE PREDICTIONS WITH PARADIGM (DIRPP) IDENTIFIES DRUG RESISTANT CANCER CELL LINES AND PATHWAY MECHANISMS OF RESISTANCE

著者: BRUBAKER, DOUGLAS, DIFEO, ANALISA, CHEN, YANWEN, PEARL, TAYLOR, ZHAI, KAIDE, BEBEK, GURKAN, CHANCE, MARK, BARNHOLTZ-SLOAN, JILL
出版事項 2014

Finding lost genes in GWAS via integrative—omics analysis reveals novel sub-networks associated with preterm birth

著者: Brubaker, Douglas, Liu, Yu, Wang, Junye, Tan, Huiqing, Zhang, Ge, Jacobsson, Bo, Muglia, Louis, Mesiano, Sam, Chance, Mark R.
出版年 Hum Mol Genet (2016)

Cell surface integrin α5ß1 clustering negatively regulates receptor tyrosine kinase signaling in colorectal cancer cells via glycogen synthase kinase 3

著者: Starchenko, Alina, Graves-Deal, Ramona, Brubaker, Douglas, Li, Cunxi, Yang, Yuping, Singh, Bhuminder, Coffey, Robert J, Lauffenburger, Douglas A
出版年 Integr Biol (Camb) (2021)

Integrated microRNA and mRNA network analysis of the human myometrial transcriptome in the transition from quiescence to labor(),()

著者: Ackerman, William E, Buhimschi, Irina A, Brubaker, Douglas, Maxwell, Sean, Rood, Kara M, Chance, Mark R, Jing, Hongwu, Mesiano, Sam, Buhimschi, Catalin S
出版年 Biol Reprod (2018)

Coagulopathy signature precedes and predicts severity of end‐organ heat stroke pathology in a mouse model

著者: Proctor, Elizabeth A., Dineen, Shauna M., Van Nostrand, Stephen C., Kuhn, Madison K., Barrett, Christopher D., Brubaker, Douglas K., Yaffe, Michael B., Lauffenburger, Douglas A., Leon, Lisa R.
出版年 J Thromb Haemost (2020)

Proteogenomic Network Analysis of Context-Specific KRAS Signaling In Mouse-to-Human Cross-Species Translation

著者: Brubaker, Douglas K., Paulo, Joao A., Sheth, Shikha, Poulin, Emily J., Popow, Olesja, Joughin, Brian A., Strasser, Samantha Dale, Starchenko, Alina, Gygi, Steven P., Lauffenburger, Douglas A., Haigis, Kevin M.
出版年 Cell Syst (2019)

An interspecies translation model implicates integrin signaling in infliximab-resistant inflammatory bowel disease

著者: Brubaker, Douglas. K., Kumar, Manu. P., Chiswick, Evan. L., Gregg, Cecil, Starchenko, Alina, Vega, Paige. N., Southard-Smith, Austin. N., Simmons, Alan. J., Scoville, Elizabeth. A., Coburn, Lori. A., Wilson, Keith. T., Lau, Ken. S., Lauffenburger, Douglas. A.
出版年 Sci Signal (2020)

Integrated in vivo multi-omics analysis identifies p21-activated kinase signaling as a driver of colitis

著者: Lyons, Jesse, Brubaker, Douglas K., Ghazi, Phaedra C., Baldwin, Katherine R., Edwards, Amanda, Boukhali, Myriam, Strasser, Samantha Dale, Suarez-Lopez, Lucia, Lin, Yi-Jang, Yajnik, Vijay, Kissil, Joseph L., Haas, Wilhelm, Lauffenburger, Douglas A., Haigis, Kevin M.
出版年 Sci Signal (2018)

Substrate-based kinase activity inference identifies MK2 as driver of colitis

著者: Strasser, Samantha Dale, Ghazi, Phaedra C., Starchenko, Alina, Boukhali, Myriam, Edwards, Amanda, Suarez-Lopez, Lucia, Lyons, Jesse, Changelian, Paul S., Monahan, Joseph B., Jacobsen, Jon, Brubaker, Douglas K., Joughin, Brian A., Yaffe, Michael B., Haas, Wilhelm, Lauffenburger, Douglas A., Haigis, Kevin M.
出版年 Integr Biol (Camb) (2019)

Tissue-specific oncogenic activity of K-Ras(A146T)

著者: Poulin, Emily J., Bera, Asim K., Lu, Jia, Lin, Yi-Jang, Strasser, Samantha Dale, Paulo, Joao A., Huang, Tannie Q., Morales, Carolina, Yan, Wei, Cook, Joshua, Nowak, Jonathan A., Brubaker, Douglas K., Joughin, Brian A., Johnson, Christian W., DeStefanis, Rebecca A., Ghazi, Phaedra C., Gondi, Sudershan, Wales, Thomas E., Iacob, Roxana E., Bogdanova, Lana, Gierut, Jessica J., Li, Yina, Engen, John R., Perez-Mancera, Pedro A., Braun, Benjamin S., Gygi, Steven P., Lauffenburger, Douglas A., Westover, Kenneth D., Haigis, Kevin M.
出版年 Cancer Discov (2019)