Proteogenomic Network Analysis of Context-Specific KRAS Signaling In Mouse-to-Human Cross-Species Translation

The highest frequencies of KRAS mutations occur in colorectal carcinoma (CRC) and pancreatic ductal adenocarcinoma (PDAC). The ability to target downstream pathways mediating KRAS oncogenicity is limited by an incomplete understanding of the contextual cues modulating the signaling output of activat...

詳細記述

保存先:
書誌詳細
出版年:Cell Syst
主要な著者: Brubaker, Douglas K., Paulo, Joao A., Sheth, Shikha, Poulin, Emily J., Popow, Olesja, Joughin, Brian A., Strasser, Samantha Dale, Starchenko, Alina, Gygi, Steven P., Lauffenburger, Douglas A., Haigis, Kevin M.
フォーマット: Artigo
言語:Inglês
出版事項: 2019
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6816257/
https://ncbi.nlm.nih.gov/pubmed/31521603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cels.2019.07.006
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