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Inflammatory but not mitogenic contexts prime synovial fibroblasts for compensatory signaling responses to p38 inhibition
Rheumatoid arthritis (RA) is a chronic inflammatory disorder that causes joint pain, swelling, and loss of function. Development of effective new drugs has proven challenging, in part because of the complexities and interconnected nature of intracellular signaling networks, which complicate the effe...
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出版年: | Sci Signal |
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主要な著者: | , , , , |
フォーマット: | Artigo |
言語: | Inglês |
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2018
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5978689/ https://ncbi.nlm.nih.gov/pubmed/29511118 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aal1601 |
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