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Inflammatory but not mitogenic contexts prime synovial fibroblasts for compensatory signaling responses to p38 inhibition

Rheumatoid arthritis (RA) is a chronic inflammatory disorder that causes joint pain, swelling, and loss of function. Development of effective new drugs has proven challenging, in part because of the complexities and interconnected nature of intracellular signaling networks, which complicate the effe...

詳細記述

保存先:
書誌詳細
出版年:Sci Signal
主要な著者: Jones, Douglas S., Jenney, Anne P., Joughin, Brian A., Sorger, Peter K., Lauffenburger, Douglas A.
フォーマット: Artigo
言語:Inglês
出版事項: 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5978689/
https://ncbi.nlm.nih.gov/pubmed/29511118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aal1601
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