A dynamical systems model of progesterone receptor interactions with inflammation in human parturition

Por Brubaker, Douglas, Barbaro, Alethea, R. Chance, Mark, Mesiano, Sam
Publicado no BMC Syst Biol (2016)

FREQUENT SUBGRAPH MINING OF PERSONALIZED SIGNALING PATHWAY NETWORKS GROUPS PATIENTS WITH FREQUENTLY DYSREGULATED DISEASE PATHWAYS AND PREDICTS PROGNOSIS

Por Durmaz, Arda, Henderson, Tim A. D., Brubaker, Douglas, Bebek, Gurkan
Publicado no Pac Symp Biocomput (2017)

Computational translation of genomic responses from experimental model systems to humans

Por Brubaker, Douglas K., Proctor, Elizabeth A., Haigis, Kevin M., Lauffenburger, Douglas A.
Publicado no PLoS Comput Biol (2019)

Clostridioides difficile-Associated Antibiotics Alter Human Mucosal Barrier Functions by Microbiome-Independent Mechanisms

Por Kester, Jemila C., Brubaker, Douglas K., Velazquez, Jason, Wright, Charles, Lauffenburger, Douglas A., Griffith, Linda G.
Publicado no Antimicrob Agents Chemother (2020)

DRUG INTERVENTION RESPONSE PREDICTIONS WITH PARADIGM (DIRPP) IDENTIFIES DRUG RESISTANT CANCER CELL LINES AND PATHWAY MECHANISMS OF RESISTANCE

Por BRUBAKER, DOUGLAS, DIFEO, ANALISA, CHEN, YANWEN, PEARL, TAYLOR, ZHAI, KAIDE, BEBEK, GURKAN, CHANCE, MARK, BARNHOLTZ-SLOAN, JILL
Publicado em 2014

Finding lost genes in GWAS via integrative—omics analysis reveals novel sub-networks associated with preterm birth

Por Brubaker, Douglas, Liu, Yu, Wang, Junye, Tan, Huiqing, Zhang, Ge, Jacobsson, Bo, Muglia, Louis, Mesiano, Sam, Chance, Mark R.
Publicado no Hum Mol Genet (2016)

Integrated microRNA and mRNA network analysis of the human myometrial transcriptome in the transition from quiescence to labor(),()

Por Ackerman, William E, Buhimschi, Irina A, Brubaker, Douglas, Maxwell, Sean, Rood, Kara M, Chance, Mark R, Jing, Hongwu, Mesiano, Sam, Buhimschi, Catalin S
Publicado no Biol Reprod (2018)

Coagulopathy signature precedes and predicts severity of end‐organ heat stroke pathology in a mouse model

Por Proctor, Elizabeth A., Dineen, Shauna M., Van Nostrand, Stephen C., Kuhn, Madison K., Barrett, Christopher D., Brubaker, Douglas K., Yaffe, Michael B., Lauffenburger, Douglas A., Leon, Lisa R.
Publicado no J Thromb Haemost (2020)

Proteogenomic Network Analysis of Context-Specific KRAS Signaling In Mouse-to-Human Cross-Species Translation

Por Brubaker, Douglas K., Paulo, Joao A., Sheth, Shikha, Poulin, Emily J., Popow, Olesja, Joughin, Brian A., Strasser, Samantha Dale, Starchenko, Alina, Gygi, Steven P., Lauffenburger, Douglas A., Haigis, Kevin M.
Publicado no Cell Syst (2019)

An interspecies translation model implicates integrin signaling in infliximab-resistant inflammatory bowel disease

Por Brubaker, Douglas. K., Kumar, Manu. P., Chiswick, Evan. L., Gregg, Cecil, Starchenko, Alina, Vega, Paige. N., Southard-Smith, Austin. N., Simmons, Alan. J., Scoville, Elizabeth. A., Coburn, Lori. A., Wilson, Keith. T., Lau, Ken. S., Lauffenburger, Douglas. A.
Publicado no Sci Signal (2020)

Integrated in vivo multi-omics analysis identifies p21-activated kinase signaling as a driver of colitis

Por Lyons, Jesse, Brubaker, Douglas K., Ghazi, Phaedra C., Baldwin, Katherine R., Edwards, Amanda, Boukhali, Myriam, Strasser, Samantha Dale, Suarez-Lopez, Lucia, Lin, Yi-Jang, Yajnik, Vijay, Kissil, Joseph L., Haas, Wilhelm, Lauffenburger, Douglas A., Haigis, Kevin M.
Publicado no Sci Signal (2018)

Substrate-based kinase activity inference identifies MK2 as driver of colitis

Por Strasser, Samantha Dale, Ghazi, Phaedra C., Starchenko, Alina, Boukhali, Myriam, Edwards, Amanda, Suarez-Lopez, Lucia, Lyons, Jesse, Changelian, Paul S., Monahan, Joseph B., Jacobsen, Jon, Brubaker, Douglas K., Joughin, Brian A., Yaffe, Michael B., Haas, Wilhelm, Lauffenburger, Douglas A., Haigis, Kevin M.
Publicado no Integr Biol (Camb) (2019)

Tissue-specific oncogenic activity of K-Ras(A146T)

Por Poulin, Emily J., Bera, Asim K., Lu, Jia, Lin, Yi-Jang, Strasser, Samantha Dale, Paulo, Joao A., Huang, Tannie Q., Morales, Carolina, Yan, Wei, Cook, Joshua, Nowak, Jonathan A., Brubaker, Douglas K., Joughin, Brian A., Johnson, Christian W., DeStefanis, Rebecca A., Ghazi, Phaedra C., Gondi, Sudershan, Wales, Thomas E., Iacob, Roxana E., Bogdanova, Lana, Gierut, Jessica J., Li, Yina, Engen, John R., Perez-Mancera, Pedro A., Braun, Benjamin S., Gygi, Steven P., Lauffenburger, Douglas A., Westover, Kenneth D., Haigis, Kevin M.
Publicado no Cancer Discov (2019)