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A dynamical systems model of progesterone receptor interactions with inflammation in human parturition

BACKGROUND: Progesterone promotes uterine relaxation and is essential for the maintenance of pregnancy. Withdrawal of progesterone activity and increased inflammation within the uterine tissues are key triggers for parturition. Progesterone actions in myometrial cells are mediated by two progesteron...

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Pubblicato in:BMC Syst Biol
Autori principali: Brubaker, Douglas, Barbaro, Alethea, R. Chance, Mark, Mesiano, Sam
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4992259/
https://ncbi.nlm.nih.gov/pubmed/27543267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12918-016-0320-1
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