Cell surface integrin α5ß1 clustering negatively regulates receptor tyrosine kinase signaling in colorectal cancer cells via glycogen synthase kinase 3

As a key process within the tissue microenvironment, integrin signaling can influence cell functional responses to growth factor stimuli. We show here that clustering of integrin α5ß1 at the plasma membrane of colorectal cancer-derived epithelial cells modulates their ability to respond to stimulati...

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Vydáno v:Integr Biol (Camb)
Hlavní autoři: Starchenko, Alina, Graves-Deal, Ramona, Brubaker, Douglas, Li, Cunxi, Yang, Yuping, Singh, Bhuminder, Coffey, Robert J, Lauffenburger, Douglas A
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2021
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8204629/
https://ncbi.nlm.nih.gov/pubmed/34037774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/intbio/zyab009
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