A dynamical systems model of progesterone receptor interactions with inflammation in human parturition

nork Brubaker, Douglas, Barbaro, Alethea, R. Chance, Mark, Mesiano, Sam
Argitaratua izan da BMC Syst Biol (2016)

FREQUENT SUBGRAPH MINING OF PERSONALIZED SIGNALING PATHWAY NETWORKS GROUPS PATIENTS WITH FREQUENTLY DYSREGULATED DISEASE PATHWAYS AND PREDICTS PROGNOSIS

nork Durmaz, Arda, Henderson, Tim A. D., Brubaker, Douglas, Bebek, Gurkan
Argitaratua izan da Pac Symp Biocomput (2017)

Computational translation of genomic responses from experimental model systems to humans

nork Brubaker, Douglas K., Proctor, Elizabeth A., Haigis, Kevin M., Lauffenburger, Douglas A.
Argitaratua izan da PLoS Comput Biol (2019)

Clostridioides difficile-Associated Antibiotics Alter Human Mucosal Barrier Functions by Microbiome-Independent Mechanisms

nork Kester, Jemila C., Brubaker, Douglas K., Velazquez, Jason, Wright, Charles, Lauffenburger, Douglas A., Griffith, Linda G.
Argitaratua izan da Antimicrob Agents Chemother (2020)

DRUG INTERVENTION RESPONSE PREDICTIONS WITH PARADIGM (DIRPP) IDENTIFIES DRUG RESISTANT CANCER CELL LINES AND PATHWAY MECHANISMS OF RESISTANCE

nork BRUBAKER, DOUGLAS, DIFEO, ANALISA, CHEN, YANWEN, PEARL, TAYLOR, ZHAI, KAIDE, BEBEK, GURKAN, CHANCE, MARK, BARNHOLTZ-SLOAN, JILL
Argitaratua 2014

Finding lost genes in GWAS via integrative—omics analysis reveals novel sub-networks associated with preterm birth

nork Brubaker, Douglas, Liu, Yu, Wang, Junye, Tan, Huiqing, Zhang, Ge, Jacobsson, Bo, Muglia, Louis, Mesiano, Sam, Chance, Mark R.
Argitaratua izan da Hum Mol Genet (2016)

Cell surface integrin α5ß1 clustering negatively regulates receptor tyrosine kinase signaling in colorectal cancer cells via glycogen synthase kinase 3

nork Starchenko, Alina, Graves-Deal, Ramona, Brubaker, Douglas, Li, Cunxi, Yang, Yuping, Singh, Bhuminder, Coffey, Robert J, Lauffenburger, Douglas A
Argitaratua izan da Integr Biol (Camb) (2021)

Integrated microRNA and mRNA network analysis of the human myometrial transcriptome in the transition from quiescence to labor(),()

nork Ackerman, William E, Buhimschi, Irina A, Brubaker, Douglas, Maxwell, Sean, Rood, Kara M, Chance, Mark R, Jing, Hongwu, Mesiano, Sam, Buhimschi, Catalin S
Argitaratua izan da Biol Reprod (2018)

Coagulopathy signature precedes and predicts severity of end‐organ heat stroke pathology in a mouse model

nork Proctor, Elizabeth A., Dineen, Shauna M., Van Nostrand, Stephen C., Kuhn, Madison K., Barrett, Christopher D., Brubaker, Douglas K., Yaffe, Michael B., Lauffenburger, Douglas A., Leon, Lisa R.
Argitaratua izan da J Thromb Haemost (2020)

Proteogenomic Network Analysis of Context-Specific KRAS Signaling In Mouse-to-Human Cross-Species Translation

nork Brubaker, Douglas K., Paulo, Joao A., Sheth, Shikha, Poulin, Emily J., Popow, Olesja, Joughin, Brian A., Strasser, Samantha Dale, Starchenko, Alina, Gygi, Steven P., Lauffenburger, Douglas A., Haigis, Kevin M.
Argitaratua izan da Cell Syst (2019)

An interspecies translation model implicates integrin signaling in infliximab-resistant inflammatory bowel disease

nork Brubaker, Douglas. K., Kumar, Manu. P., Chiswick, Evan. L., Gregg, Cecil, Starchenko, Alina, Vega, Paige. N., Southard-Smith, Austin. N., Simmons, Alan. J., Scoville, Elizabeth. A., Coburn, Lori. A., Wilson, Keith. T., Lau, Ken. S., Lauffenburger, Douglas. A.
Argitaratua izan da Sci Signal (2020)

Integrated in vivo multi-omics analysis identifies p21-activated kinase signaling as a driver of colitis

nork Lyons, Jesse, Brubaker, Douglas K., Ghazi, Phaedra C., Baldwin, Katherine R., Edwards, Amanda, Boukhali, Myriam, Strasser, Samantha Dale, Suarez-Lopez, Lucia, Lin, Yi-Jang, Yajnik, Vijay, Kissil, Joseph L., Haas, Wilhelm, Lauffenburger, Douglas A., Haigis, Kevin M.
Argitaratua izan da Sci Signal (2018)

Substrate-based kinase activity inference identifies MK2 as driver of colitis

nork Strasser, Samantha Dale, Ghazi, Phaedra C., Starchenko, Alina, Boukhali, Myriam, Edwards, Amanda, Suarez-Lopez, Lucia, Lyons, Jesse, Changelian, Paul S., Monahan, Joseph B., Jacobsen, Jon, Brubaker, Douglas K., Joughin, Brian A., Yaffe, Michael B., Haas, Wilhelm, Lauffenburger, Douglas A., Haigis, Kevin M.
Argitaratua izan da Integr Biol (Camb) (2019)

Tissue-specific oncogenic activity of K-Ras(A146T)

nork Poulin, Emily J., Bera, Asim K., Lu, Jia, Lin, Yi-Jang, Strasser, Samantha Dale, Paulo, Joao A., Huang, Tannie Q., Morales, Carolina, Yan, Wei, Cook, Joshua, Nowak, Jonathan A., Brubaker, Douglas K., Joughin, Brian A., Johnson, Christian W., DeStefanis, Rebecca A., Ghazi, Phaedra C., Gondi, Sudershan, Wales, Thomas E., Iacob, Roxana E., Bogdanova, Lana, Gierut, Jessica J., Li, Yina, Engen, John R., Perez-Mancera, Pedro A., Braun, Benjamin S., Gygi, Steven P., Lauffenburger, Douglas A., Westover, Kenneth D., Haigis, Kevin M.
Argitaratua izan da Cancer Discov (2019)