Therapeutic potential of neuropeptide Y (NPY) receptor ligands

Por Brothers, Shaun P, Wahlestedt, Claes
Publicado em 2010

Orphan Diseases: State of the Drug Discovery Art

Por Volmar, Claude-Henry, Wahlestedt, Claes, Brothers, Shaun
Publicado no Wien Med Wochenschr (2016)

I-BET151 selectively regulates IL-6 production

Por Barrett, Elyse, Brothers, Shaun, Wahlestedt, Claes, Beurel, Eléonore
Publicado em 2014

Emerging treatment strategies for glioblastoma multiforme

Por Carlsson, Steven K, Brothers, Shaun P, Wahlestedt, Claes
Publicado no EMBO Mol Med (2014)

Oxytocin and social functioning

Por Jones, Candace, Barrera, Ingrid, Brothers, Shaun, Ring, Robert, Wahlestedt, Claes
Publicado no Dialogues Clin Neurosci (2017)

Epigenetic Readers of Lysine Acetylation Regulate Cocaine-Induced Plasticity

Por Sartor, Gregory C., Powell, Samuel K., Brothers, Shaun P., Wahlestedt, Claes
Publicado no J Neurosci (2015)

Differential Effects of the Gβ5-RGS7 Complex on Muscarinic M3 Receptor–Induced Ca(2+) Influx and Release

Por Karpinsky-Semper, Darla, Volmar, Claude-Henry, Brothers, Shaun P., Slepak, Vladlen Z.
Publicado em 2014

A Novel RNA Transcript with Antiapoptotic Function Is Silenced in Fragile X Syndrome

Por Khalil, Ahmad M., Faghihi, Mohammad Ali, Modarresi, Farzaneh, Brothers, Shaun P., Wahlestedt, Claes
Publicado em 2008

Synthesis and SAR of selective small molecule Neuropeptide Y Y2 receptor antagonists

Por Mittapalli, Gopi Kumar, Vellucci, Danielle, Yang, Jun, Toussaint, Marion, Brothers, Shaun P, Wahlestedt, Claes, Roberts, Edward
Publicado em 2012

EG-04 DEVELOPMENT OF HIGHLY POTENT, SELECTIVE BET BROMODOMAIN INHIBITORS THAT ARE CNS PENETRANT AND EFFECTIVE IN RODENT MODELS OF BRAIN CANCER

Por Johnstone, Shawn, Johhnsone, Andrea, Penas, Clara, Stathias, Vasileios, Brothers, Shaun, Ayad, Nagi, Wahlestedt, Claes, Albert, Jeffrey
Publicado em 2014

The nociceptin/orphanin FQ receptor agonist SR-8993 as a candidate therapeutic for alcohol use disorders: validation in rat models

Por Aziz, Abdul Maruf Asif, Brothers, Shaun, Sartor, Gregory, Holm, Lovisa, Heilig, Markus, Wahlestedt, Claes, Thorsell, Annika
Publicado no Psychopharmacology (Berl) (2016)

Selective and Brain Penetrant Neuropeptide Y Y2 Receptor Antagonists Discovered by Whole-Cell High-Throughput Screening

Por Brothers, Shaun P., Saldanha, S. Adrian, Spicer, Timothy P., Cameron, Michael, Mercer, Becky A., Chase, Peter, McDonald, Patricia, Wahlestedt, Claes, Hodder, Peter S.
Publicado em 2010

RNAi Screen Indicates Widespread Biological Function for Human Natural Antisense Transcripts

Por Faghihi, Mohammad Ali, Kocerha, Jannet, Modarresi, Farzaneh, Engström, Pär G., Chalk, Alistair M., Brothers, Shaun P., Koesema, Eric, St. Laurent, Georges, Wahlestedt, Claes
Publicado em 2010

Epigenetic regulation of embryonic stem cell marker miR302C in human chondrosarcoma as determinant of antiproliferative activity of proline-rich polypeptide 1

Por GALOIAN, KARINA, QURESHI, AMIR, D’IPPOLITO, GIANLUCA, SCHILLER, PAUL C., MOLINARI, MARCO, JOHNSTONE, ANDREA L., BROTHERS, SHAUN P., PAZ, ANA C., TEMPLE, H.T.
Publicado no Int J Oncol (2015)

Vitamin C sensitizes melanoma to BET inhibitors

Por Mustafi, Sushmita, Camarena, Vladimir, Volmar, Claude-Henry, Huff, Tyler C., Sant, David W., Brothers, Shaun P., Liu, Zhao-Jun, Wahlestedt, Claes, Wang, Gaofeng
Publicado no Cancer Res (2017)

REFOLDING OF MISFOLDED MUTANT GPCR: POST-TRANSLATIONAL PHARMACOPERONE ACTION IN VITRO

Por Janovick, Jo Ann, Brothers, Shaun P., Cornea, Anda, Bush, Eugene, Goulet, Mark T., Ashton, Wallace T., Sauer, Daryl R., Haviv, Fortuna, Greer, Jonathan, Conn, P. Michael
Publicado em 2007

Natural Antisense Inhibition Results in Transcriptional De-Repression and Gene Upregulation

Por Modarresi, Farzaneh, Faghihi, Mohammad Ali, Lopez-Toledano, Miguel A., Fatemi, Roya Pedram, Magistri, Marco, Brothers, Shaun P., van der Brug, Marcel P., Wahlestedt, Claes
Publicado em 2012

Amygdala-Dependent Fear Is Regulated by Oprl1 in Mice and Humans with PTSD

Por Andero, Raül, Brothers, Shaun P., Jovanovic, Tanja, Chen, Yen T., Salah-Uddin, Hasib, Cameron, Michael, Bannister, Thomas D., Almli, Lynn, Stevens, Jennifer S., Bradley, Bekh, Binder, Elisabeth B., Wahlestedt, Claes, Ressler, Kerry J.
Publicado em 2013

BET bromodomain proteins are required for glioblastoma cell proliferation

Por Pastori, Chiara, Daniel, Mark, Penas, Clara, Volmar, Claude-Henry, Johnstone, Andrea L, Brothers, Shaun P, Graham, Regina M, Allen, Bryce, Sarkaria, Jann N, Komotar, Ricardo J, Wahlestedt, Claes, Ayad, Nagi G
Publicado em 2014

Systemic reprograming of translation efficiencies on oxygen stimulus

Por Ho, J.J. David, Wang, Miling, Audas, Timothy E., Kwon, Deukwoo, Carlsson, Steven K., Timpano, Sara, Evagelou, Sonia L., Brothers, Shaun, Gonzalgo, Mark L., Krieger, Jonathan R., Chen, Steven, Uniacke, James, Lee, Stephen
Publicado no Cell Rep (2016)