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Systemic reprograming of translation efficiencies on oxygen stimulus

Protein concentrations evolve under greater evolutionary constraint than mRNA levels. Translation efficiency of mRNA represents the chief determinant of basal protein concentrations. This raises a fundamental question of how mRNA and protein levels are coordinated in dynamic systems responding to ph...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Ho, J.J. David, Wang, Miling, Audas, Timothy E., Kwon, Deukwoo, Carlsson, Steven K., Timpano, Sara, Evagelou, Sonia L., Brothers, Shaun, Gonzalgo, Mark L., Krieger, Jonathan R., Chen, Steven, Uniacke, James, Lee, Stephen
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4758860/
https://ncbi.nlm.nih.gov/pubmed/26854219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.01.036
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