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Systemic reprograming of translation efficiencies on oxygen stimulus
Protein concentrations evolve under greater evolutionary constraint than mRNA levels. Translation efficiency of mRNA represents the chief determinant of basal protein concentrations. This raises a fundamental question of how mRNA and protein levels are coordinated in dynamic systems responding to ph...
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Publicado no: | Cell Rep |
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Main Authors: | , , , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4758860/ https://ncbi.nlm.nih.gov/pubmed/26854219 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.01.036 |
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