Semi-synthesis of ubiquitinated histone H2B with a native or non-hydrolyzable linkage

af Morgan, Michael, Jbara, Muhammad, Brik, Ashraf, Wolberger, Cynthia
Udgivet i Methods Enzymol (2019)

Enhanced Live‐Cell Delivery of Synthetic Proteins Assisted by Cell‐Penetrating Peptides Fused to DABCYL

af Mandal, Shaswati, Mann, Guy, Satish, Gandhesiri, Brik, Ashraf
Udgivet i Angew Chem Int Ed Engl (2021)

Total chemical synthesis of ester-linked ubiquitinated proteins unravels their behavior with deubiquitinases

af Sun, Hao, Meledin, Roman, Mali, Sachitanand M., Brik, Ashraf
Udgivet i Chem Sci (2018)

Sugar-Assisted Ligation in Glycoprotein Synthesis

af Yang, Yu-Ying, Ficht, Simon, Brik, Ashraf, Wong, Chi-Huey
Udgivet 2007

Understanding and predicting the potency of ROS-based enzyme inhibitors, exemplified by naphthoquinones and ubiquitin specific protease-2

af Gopinath, Pushparathinam, Mahammed, Atif, Ohayon, Shimrit, Gross, Zeev, Brik, Ashraf
Udgivet i Chem Sci (2016)

Examining the role of phosphorylation of p19(INK4d) in its stability and ubiquitination using chemical protein synthesis

af Msallam, Muna, Sun, Hao, Meledin, Roman, Franz, Pauline, Brik, Ashraf
Udgivet i Chem Sci (2020)

General synthetic strategy for regioselective ultrafast formation of disulfide bonds in peptides and proteins

af Laps, Shay, Atamleh, Fatima, Kamnesky, Guy, Sun, Hao, Brik, Ashraf
Udgivet i Nat Commun (2021)

Model System for High-Throughput Screening of Novel Human Immunodeficiency Virus Protease Inhibitors in Escherichia coli

af Cheng, Ting-Jen, Brik, Ashraf, Wong, Chi-Huey, Kan, Chen-Chen
Udgivet 2004

Total Chemical Synthesis of Phosphorylated Histone H2A at Tyr57 Reveals Insight into the Inhibition Mode of the SAGA Deubiquitinating Module

af Jbara, Muhammad, Maity, Suman Kumar, Morgan, Michael, Wolberger, Cynthia, Brik, Ashraf
Udgivet i Angew Chem Int Ed Engl (2016)

Total chemical synthesis of SUMO-2-Lys63-linked diubiquitin hybrid chains assisted by removable solubilizing tags

af Bondalapati, Somasekhar, Eid, Emad, Mali, Sachitanand M., Wolberger, Cynthia, Brik, Ashraf
Udgivet i Chem Sci (2017)

Tetrabutylammonium fluoride-assisted rapid N(9)-alkylation on purine ring: Application to combinatorial reactions in microtiter plates for the discovery of potent sulfotransferase...

af Brik, Ashraf, Wu, Chung-Yi, Best, Michael D., Wong, Chi-Huey
Udgivet i Bioorg Med Chem (2005)

The Development of a Fluorescence‐Based Competitive Assay Enabled the Discovery of Dimeric Cyclic Peptide Modulators of Ubiquitin Chains

af Vamisetti, Ganga B., Meledin, Roman, Nawatha, Mickal, Suga, Hiroaki, Brik, Ashraf
Udgivet i Angew Chem Int Ed Engl (2021)

Segmental Isotopic Labelling of Ubiquitin Chains to Unravel Monomer-Specific Molecular Behavior ()

af Castañeda, Carlos A., Spasser, Liat, Bavikar, Sudhir N., Brik, Ashraf, Fushman, David
Udgivet 2011

N-Methylcysteine-Mediated Total Chemical Synthesis of Ubiquitin Thioester

af Erlich, Lesly A., Ajish Kumar, K. S., Haj-Yahya, Mahmood, Dawson, Philip E., Brik, Ashraf
Udgivet 2010

Structural basis for histone H2B deubiquitination by the SAGA DUB module

af Morgan, Michael T., Haj-Yahya, Mahmood, Ringel, Alison E., Bandi, Prasanthi, Brik, Ashraf, Wolberger, Cynthia
Udgivet i Science (2016)

Palladium prompted on-demand cysteine chemistry for the synthesis of challenging and uniquely modified proteins

af Jbara, Muhammad, Laps, Shay, Morgan, Michael, Kamnesky, Guy, Mann, Guy, Wolberger, Cynthia, Brik, Ashraf
Udgivet i Nat Commun (2018)

Total Chemical Synthesis of ISGylated-Ubiquitin Hybrid Chain Assisted by Acetamidomethyl Derivatives with Dual Functions

af Eid, Emad, Boross, Gábor N., Sun, Hao, Msallam, Muna, Singh, Sumeet K., Brik, Ashraf
Udgivet i Bioconjug Chem (2020)

On-Demand Detachment of Succinimides on Cysteine to Facilitate (Semi)Synthesis of Challenging Proteins

af Vamisetti, Ganga B., Satish, Gandhesiri, Sulkshane, Prasad, Mann, Guy, Glickman, Michael H., Brik, Ashraf
Udgivet i J Am Chem Soc (2020)

Sugar-Assisted Glycopeptide Ligation with Complex Oligosaccharides: Scope and Limitations

af Bennett, Clay S., Dean, Stephen M., Payne, Richard J., Ficht, Simon, Brik, Ashraf, Wong, Chi-Huey
Udgivet 2008

The U4/U6 Recycling Factor SART3 Has Histone Chaperone Activity and Associates with USP15 to Regulate H2B Deubiquitination

af Long, Lindsey, Thelen, Joseph P., Furgason, Melonnie, Haj-Yahya, Mahmood, Brik, Ashraf, Cheng, Dongmei, Peng, Junmin, Yao, Tingting
Udgivet 2014