Total Chemical Synthesis of ISGylated-Ubiquitin Hybrid Chain Assisted by Acetamidomethyl Derivatives with Dual Functions

von Eid, Emad, Boross, Gábor N., Sun, Hao, Msallam, Muna, Singh, Sumeet K., Brik, Ashraf
Veröffentlicht in Bioconjug Chem (2020)

Diverse fate of ubiquitin chain moieties: The proximal is degraded with the target, and the distal protects the proximal from removal and recycles

von Sun, Hao, Mali, Sachitanand M., Singh, Sumeet K., Meledin, Roman, Brik, Ashraf, Kwon, Yong Tae, Kravtsova-Ivantsiv, Yelena, Bercovich, Beatrice, Ciechanover, Aaron
Veröffentlicht in Proc Natl Acad Sci U S A (2019)