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Palladium prompted on-demand cysteine chemistry for the synthesis of challenging and uniquely modified proteins

Organic chemistry allows for the modification and chemical preparation of protein analogues for various studies. The thiolate side chain of the Cys residue has been a key functionality in these ventures. In order to generate complex molecular targets, there is a particular need to incorporate orthog...

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Библиографические подробности
Опубликовано в: :Nat Commun
Главные авторы: Jbara, Muhammad, Laps, Shay, Morgan, Michael, Kamnesky, Guy, Mann, Guy, Wolberger, Cynthia, Brik, Ashraf
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2018
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6082840/
https://ncbi.nlm.nih.gov/pubmed/30089783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-05628-0
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