Cargando...

FACT and Ubp10 collaborate to modulate H2B deubiquitination and nucleosome dynamics

Monoubiquitination of histone H2B (H2B-Ub) plays a role in transcription and DNA replication, and is required for normal localization of the histone chaperone, FACT. In yeast, H2B-Ub is deubiquitinated by Ubp8, a subunit of SAGA, and Ubp10. Although they target the same substrate, loss of Ubp8 and U...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:eLife
Autores principales: Nune, Melesse, Morgan, Michael T, Connell, Zaily, McCullough, Laura, Jbara, Muhammad, Sun, Hao, Brik, Ashraf, Formosa, Tim, Wolberger, Cynthia
Formato: Artigo
Lenguaje:Inglês
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6372288/
https://ncbi.nlm.nih.gov/pubmed/30681413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.40988
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!