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Total chemical synthesis of ester-linked ubiquitinated proteins unravels their behavior with deubiquitinases

Ester-linked ubiquitinated proteins have been reported by several groups to be involved in ubiquitin signalling. However, due to the lack of the suitable tools to homogeneously produce such conjugates, their exact physiological roles and biochemical behavior remain enigmatic. Here, we report for the...

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Библиографические подробности
Опубликовано в: :Chem Sci
Главные авторы: Sun, Hao, Meledin, Roman, Mali, Sachitanand M., Brik, Ashraf
Формат: Artigo
Язык:Inglês
Опубликовано: Royal Society of Chemistry 2018
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5887810/
https://ncbi.nlm.nih.gov/pubmed/29675213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7sc04518b
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