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Total chemical synthesis of ester-linked ubiquitinated proteins unravels their behavior with deubiquitinases

Ester-linked ubiquitinated proteins have been reported by several groups to be involved in ubiquitin signalling. However, due to the lack of the suitable tools to homogeneously produce such conjugates, their exact physiological roles and biochemical behavior remain enigmatic. Here, we report for the...

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Sun, Hao, Meledin, Roman, Mali, Sachitanand M., Brik, Ashraf
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5887810/
https://ncbi.nlm.nih.gov/pubmed/29675213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7sc04518b
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