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Examining the role of phosphorylation of p19(INK4d) in its stability and ubiquitination using chemical protein synthesis

p19(INK4d) plays an important role in the regulation of the cell cycle by inhibiting the function of cyclin-dependent kinases 4/6 that is responsible for the phosphorylation and deactivation of the retinoblastoma protein (pRb) tumour suppressor. Recently, it was reported that phosphorylation of p19(...

詳細記述

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書誌詳細
出版年:Chem Sci
主要な著者: Msallam, Muna, Sun, Hao, Meledin, Roman, Franz, Pauline, Brik, Ashraf
フォーマット: Artigo
言語:Inglês
出版事項: Royal Society of Chemistry 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7446725/
https://ncbi.nlm.nih.gov/pubmed/32874495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9sc06300e
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