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Structural basis for histone H2B deubiquitination by the SAGA DUB module

Monoubiquitinated histone H2B plays multiple roles in transcription activation. H2B is deubiquitinated by the Spt-Ada-Gcn5 acetyltransferase (SAGA) coactivator, which contains a four-protein subcomplex known as the deubiquitinating (DUB) module. The crystal structure of the Ubp8/Sgf11/Sus1/Sgf73 DUB...

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Detaylı Bibliyografya
Yayımlandı:Science
Asıl Yazarlar: Morgan, Michael T., Haj-Yahya, Mahmood, Ringel, Alison E., Bandi, Prasanthi, Brik, Ashraf, Wolberger, Cynthia
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2016
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4863942/
https://ncbi.nlm.nih.gov/pubmed/26912860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aac5681
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