Characteristics and homogeneity of N6-methylation in human genomes

door Pacini, Clare E., Bradshaw, Charles R., Garrett, Nigel J., Koziol, Magdalena J.
Gepubliceerd in Sci Rep (2019)

CDK phosphorylation of SLD-2 is required for replication initiation and germline development in C. elegans

door Gaggioli, Vincent, Zeiser, Eva, Rivers, David, Bradshaw, Charles R., Ahringer, Julie, Zegerman, Philip
Gepubliceerd in 2014

Titration of Four Replication Factors is essential for the Xenopus laevis Mid-Blastula Transition

door Collart, Clara, Allen, George E., Bradshaw, Charles R., Smith, James C., Zegerman, Philip
Gepubliceerd in 2013

CDK phosphorylation of SLD-2 is required for replication initiation and germline development in C. elegans

door Gaggioli, Vincent, Zeiser, Eva, Rivers, David, Bradshaw, Charles R., Ahringer, Julie, Zegerman, Philip
Gepubliceerd in 2014

Nuclear Wave1 Is Required for Reprogramming Transcription in Oocytes and for Normal Development

door Miyamoto, Kei, Teperek, Marta, Yusa, Kosuke, Allen, George E, Bradshaw, Charles R, Gurdon, J. B.
Gepubliceerd in 2013

Identification of Methylated Deoxyadenosines in Genomic DNA by dA(6m) DNA Immunoprecipitation

door Koziol, Magdalena J., Bradshaw, Charles R., Allen, George E., Costa, Ana S.H., Frezza, Christian
Gepubliceerd in Bio Protoc (2016)

H3K4 Methylation-Dependent Memory of Somatic Cell Identity Inhibits Reprogramming and Development of Nuclear Transfer Embryos

door Hörmanseder, Eva, Simeone, Angela, Allen, George E., Bradshaw, Charles R., Figlmüller, Magdalena, Gurdon, John, Jullien, Jerome
Gepubliceerd in Cell Stem Cell (2017)

Histone H3 lysine 9 trimethylation is required for suppressing the expression of an embryonically activated retrotransposon in Xenopus laevis

door Herberg, Sarah, Simeone, Angela, Oikawa, Mami, Jullien, Jerome, Bradshaw, Charles R, Teperek, Marta, Gurdon, John, Miyamoto, Kei
Gepubliceerd in Sci Rep (2015)

Identification of methylated deoxyadenosines in vertebrates reveals diversity in DNA modifications

door Koziol, Magdalena J., Bradshaw, Charles R., Allen, George E., Costa, Ana S.H., Frezza, Christian, Gurdon, John B.
Gepubliceerd in Nat Struct Mol Biol (2015)

Replication stress induces 53BP1-containing OPT domains in G1 cells

door Harrigan, Jeanine A., Belotserkovskaya, Rimma, Coates, Julia, Dimitrova, Daniela S., Polo, Sophie E., Bradshaw, Charles R., Fraser, Peter, Jackson, Stephen P.
Gepubliceerd in 2011

Small molecule-induced DNA damage identifies alternative DNA structures in human genes

door Rodriguez, Raphaël, Miller, Kyle M., Forment, Josep V., Bradshaw, Charles R., Nikan, Mehran, Britton, Sébastien, Oelschlaegel, Tobias, Xhemalce, Blerta, Balasubramanian, Shankar, Jackson, Stephen P.
Gepubliceerd in 2012

Chromatin Accessibility Impacts Transcriptional Reprogramming in Oocytes

door Miyamoto, Kei, Nguyen, Khoi T., Allen, George E., Jullien, Jerome, Kumar, Dinesh, Otani, Tomoki, Bradshaw, Charles R., Livesey, Frederick J., Kellis, Manolis, Gurdon, John B.
Gepubliceerd in Cell Rep (2018)

Hierarchical Molecular Events Driven by Oocyte-Specific Factors Lead to Rapid and Extensive Reprogramming

door Jullien, Jerome, Miyamoto, Kei, Pasque, Vincent, Allen, George E., Bradshaw, Charles R., Garrett, Nigel J., Halley-Stott, Richard P., Kimura, Hiroshi, Ohsumi, Keita, Gurdon, John B.
Gepubliceerd in 2014

A Unique Gene Regulatory Network Resets the Human Germline Epigenome for Development

door Tang, Walfred W.C., Dietmann, Sabine, Irie, Naoko, Leitch, Harry G., Floros, Vasileios I., Bradshaw, Charles R., Hackett, Jamie A., Chinnery, Patrick F., Surani, M. Azim
Gepubliceerd in Cell (2015)

Mechanical cell competition kills cells via induction of lethal p53 levels

door Wagstaff, Laura, Goschorska, Maja, Kozyrska, Kasia, Duclos, Guillaume, Kucinski, Iwo, Chessel, Anatole, Hampton-O'Neil, Lea, Bradshaw, Charles R., Allen, George E., Rawlins, Emma L., Silberzan, Pascal, Carazo Salas, Rafael E., Piddini, Eugenia
Gepubliceerd in Nat Commun (2016)

Sperm is epigenetically programmed to regulate gene transcription in embryos

door Teperek, Marta, Simeone, Angela, Gaggioli, Vincent, Miyamoto, Kei, Allen, George E., Erkek, Serap, Kwon, Taejoon, Marcotte, Edward M., Zegerman, Philip, Bradshaw, Charles R., Peters, Antoine H.F.M., Gurdon, John B., Jullien, Jerome
Gepubliceerd in Genome Res (2016)

Reprogramming towards totipotency is greatly facilitated by synergistic effects of small molecules

door Miyamoto, Kei, Tajima, Yosuke, Yoshida, Koki, Oikawa, Mami, Azuma, Rika, Allen, George E., Tsujikawa, Tomomi, Tsukaguchi, Tomomasa, Bradshaw, Charles R., Jullien, Jerome, Yamagata, Kazuo, Matsumoto, Kazuya, Anzai, Masayuki, Imai, Hiroshi, Gurdon, John B., Yamada, Masayasu
Gepubliceerd in Biol Open (2017)

A direct role for SNX9 in the biogenesis of filopodia

door Jarsch, Iris K., Gadsby, Jonathan R., Nuccitelli, Annalisa, Mason, Julia, Shimo, Hanae, Pilloux, Ludovic, Marzook, Bishara, Mulvey, Claire M., Dobramysl, Ulrich, Bradshaw, Charles R., Lilley, Kathryn S., Hayward, Richard D., Vaughan, Tristan J., Dobson, Claire L., Gallop, Jennifer L.
Gepubliceerd in J Cell Biol (2020)

Epigenetic homogeneity in histone methylation underlies sperm programming for embryonic transcription

door Oikawa, Mami, Simeone, Angela, Hormanseder, Eva, Teperek, Marta, Gaggioli, Vincent, O’Doherty, Alan, Falk, Emma, Sporniak, Matthieu, D’Santos, Clive, Franklin, Valar Nila Roamio, Kishore, Kamal, Bradshaw, Charles R., Keane, Declan, Freour, Thomas, David, Laurent, Grzybowski, Adrian T., Ruthenburg, Alexander J., Gurdon, John, Jullien, Jerome
Gepubliceerd in Nat Commun (2020)

Human Primary Liver Cancer -derived Organoid Cultures for disease modelling and drug screening

door Broutier, Laura, Mastrogiovanni, Gianmarco, Verstegen, Monique M.A., Francies, Hayley E., Gavarró, Lena Morrill, Bradshaw, Charles R, Allen, George E, Arnes-Benito, Robert, Sidorova, Olga, Gaspersz, Marcia P., Georgakopoulos, Nikitas, Koo, Bon-Kyoung, Dietmann, Sabine, Davies, Susan E., Praseedom, Raaj K., Lieshout, Ruby, IJzermans, Jan N. M., Wigmore, Stephen J, Saeb-Parsy, Kourosh, Garnett, Mathew J., van der Laan, Luc J.W., Huch, Meritxell
Gepubliceerd in Nat Med (2017)