Sperm is epigenetically programmed to regulate gene transcription in embryos

For a long time, it has been assumed that the only role of sperm at fertilization is to introduce the male genome into the egg. Recently, ideas have emerged that the epigenetic state of the sperm nucleus could influence transcription in the embryo. However, conflicting reports have challenged the ex...

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Vydáno v:Genome Res
Hlavní autoři: Teperek, Marta, Simeone, Angela, Gaggioli, Vincent, Miyamoto, Kei, Allen, George E., Erkek, Serap, Kwon, Taejoon, Marcotte, Edward M., Zegerman, Philip, Bradshaw, Charles R., Peters, Antoine H.F.M., Gurdon, John B., Jullien, Jerome
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2016
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4971762/
https://ncbi.nlm.nih.gov/pubmed/27034506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.201541.115
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