Sperm is epigenetically programmed to regulate gene transcription in embryos

For a long time, it has been assumed that the only role of sperm at fertilization is to introduce the male genome into the egg. Recently, ideas have emerged that the epigenetic state of the sperm nucleus could influence transcription in the embryo. However, conflicting reports have challenged the ex...

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Detalhes bibliográficos
Publicado no:Genome Res
Main Authors: Teperek, Marta, Simeone, Angela, Gaggioli, Vincent, Miyamoto, Kei, Allen, George E., Erkek, Serap, Kwon, Taejoon, Marcotte, Edward M., Zegerman, Philip, Bradshaw, Charles R., Peters, Antoine H.F.M., Gurdon, John B., Jullien, Jerome
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4971762/
https://ncbi.nlm.nih.gov/pubmed/27034506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.201541.115
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