Chromatin Accessibility Impacts Transcriptional Reprogramming in Oocytes

Oocytes have a remarkable ability to reactivate silenced genes in somatic cells. However, it is not clear how the chromatin architecture of somatic cells affects this transcriptional reprogramming. Here, we investigated the relationship between the chromatin opening and transcriptional activation. W...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Miyamoto, Kei, Nguyen, Khoi T., Allen, George E., Jullien, Jerome, Kumar, Dinesh, Otani, Tomoki, Bradshaw, Charles R., Livesey, Frederick J., Kellis, Manolis, Gurdon, John B.
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6057489/
https://ncbi.nlm.nih.gov/pubmed/29996092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.06.030
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